Publications
The Chaperone FACT and Histone H2B Ubiquitination Maintain S. pombe Genome Architecture through Genic and Subtelomeric Functions. Mol Cell. 2020 ;77(3):501-513.e7.
. Chromatin as a key consumer in the metabolite economy. Nat Chem Biol. 2020 ;16(6):620-629.
. Impaired cell fate through gain-of-function mutations in a chromatin reader. Nature. 2020 ;577(7788):121-126.
. In situ chromatin interactomics using a chemical bait and trap approach. Nat Chem. 2020 ;12(6):520-527.
. Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin. Proc Natl Acad Sci U S A. 2020 ;117(48):30465-30475.
. BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila. Nat Commun. 2019 ;10(1):5700.
. Centromere RNA Is Negatively Regulated by Cbf1 and Its Unscheduled Synthesis Impacts CenH3 Binding. Genetics. 2019 ;213(2):465-479.
. Distinct Elements Confer the Blocking and Bypass Functions of the Bithorax Boundary. Genetics. 2019 ;213(3):865-876.
. JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila. Nat Commun. 2019 ;10(1):5343.
. PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism. Nat Commun. 2019 ;10(1):2146.
. Acetylation blocks DNA damage-induced chromatin ADP-ribosylation. Nat Chem Biol. 2018 ;14(9):837-840.
. The bithorax complex iab-7 Polycomb response element has a novel role in the functioning of the Fab-7 chromatin boundary. PLoS Genet. 2018 ;14(8):e1007442.
. Crosstalk among Set1 complex subunits involved in H2B ubiquitylation-dependent H3K4 methylation. Nucleic Acids Res. 2018 ;46(21):11129-11143.
. Dynamic interplay between enhancer-promoter topology and gene activity. Nat Genet. 2018 ;50(9):1296-1303.
. HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome. Proc Natl Acad Sci U S A. 2018 ;115(5):E876-E885.
. Initiating Events in Direct Cardiomyocyte Reprogramming. Cell Rep. 2018 ;22(7):1913-1922.
. Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome. Cell. 2018 ;175(6):1481-1491.e13.
. Paip2 is localized to active promoters and loaded onto nascent mRNA in Drosophila. Cell Cycle. 2018 ;17(14):1708-1720.
. Boundaries of loop domains (insulators): Determinants of chromosome form and function in multicellular eukaryotes. Bioessays. 2017 ;39(3).
. . Different Evolutionary Strategies To Conserve Chromatin Boundary Function in the Bithorax Complex. Genetics. 2017 ;205(2):589-603.
. Emerging Chemistry Strategies for Engineering Native Chromatin. J Am Chem Soc. 2017 ;139(27):9090-9096.
. The GAGA factor regulatory network: Identification of GAGA factor associated proteins. PLoS One. 2017 ;12(3):e0173602.
. Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA. Nat Struct Mol Biol. 2017 ;24(12):1028-1038.
. Red Blood Cell Invasion by the Malaria Parasite Is Coordinated by the PfAP2-I Transcription Factor. Cell Host Microbe. 2017 ;21(6):731-741.e10.
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