Publications
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Author Title [ Year
Filters: Keyword is Metabolic Networks and Pathways [Clear All Filters]
Physiological limitations and opportunities in microbial metabolic engineering. Nat Rev Microbiol. 2022 ;20(1):35-48.
. Dynamical Modeling of Optogenetic Circuits in Yeast for Metabolic Engineering Applications. ACS Synth Biol. 2021 ;10(2):219-227.
. Metabolic channeling: predictions, deductions, and evidence. Mol Cell. 2021 ;81(18):3775-3785.
. Metabolic decisions in development and disease-a Keystone Symposia report. Ann N Y Acad Sci. 2021 ;1506(1):55-73.
. Methionine synthase supports tumour tetrahydrofolate pools. Nat Metab. 2021 ;3(11):1512-1520.
. Optogenetic Amplification Circuits for Light-Induced Metabolic Control. ACS Synth Biol. 2021 ;10(5):1143-1154.
. Quantitative flux analysis in mammals. Nat Metab. 2021 ;3(7):896-908.
. Serine catabolism generates liver NADPH and supports hepatic lipogenesis. Nat Metab. 2021 ;3(12):1608-1620.
. Chemical Embryology Redux: Metabolic Control of Development. Trends Genet. 2020 ;36(8):577-586.
. Chromatin as a key consumer in the metabolite economy. Nat Chem Biol. 2020 ;16(6):620-629.
. Metabolic excretion associated with nutrient-growth dysregulation promotes the rapid evolution of an overt metabolic defect. PLoS Biol. 2020 ;18(8):e3000757.
. Optogenetics and biosensors set the stage for metabolic cybergenetics. Curr Opin Biotechnol. 2020 ;65:296-309.
. ¡Viva la mitochondria!: harnessing yeast mitochondria for chemical production. FEMS Yeast Res. 2020 ;20(6).
. Light-based control of metabolic flux through assembly of synthetic organelles. Nat Chem Biol. 2019 ;15(6):589-597.
. Mechanical Genomic Studies Reveal the Role of d-Alanine Metabolism in Pseudomonas aeruginosa Cell Stiffness. mBio. 2018 ;9(5).
. Optogenetic regulation of engineered cellular metabolism for microbial chemical production. Nature. 2018 ;555(7698):683-687.
. One-Carbon Metabolism in Health and Disease. Cell Metab. 2017 ;25(1):27-42.
. Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin. Clin Cancer Res. 2017 ;23(18):5639-5647.
. Intricate Roles of Mammalian Sirtuins in Defense against Viral Pathogens. J Virol. 2016 ;90(1):5-8.
. Lipopolysaccharide transport and assembly at the outer membrane: the PEZ model. Nat Rev Microbiol. 2016 ;14(6):337-45.
. Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans. Elife. 2016 ;5.
. Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation. Cell Metab. 2016 ;24(1):104-17.
. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metab. 2016 ;23(6):1140-1153.
. Systems-level analysis of mechanisms regulating yeast metabolic flux. Science. 2016 ;354(6311).
. A Kinetic Platform to Determine the Fate of Hydrogen Peroxide in Escherichia coli. PLoS Comput Biol. 2015 ;11(11):e1004562.
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