Publications
Molecular systematics of the butterfly genus Ithomia (Lepidoptera: Ithomiinae): a composite phylogenetic hypothesis based on seven genes. Mol Phylogenet Evol. 2005 ;34(3):625-44.
. Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols. Nat Biotechnol. 2013 ;31(4):335-41.
. Structural investigation of the proton-coupled secondary transporters. Curr Opin Struct Biol. 2013 ;23(4):483-91.
. Host control of symbiont natural product chemistry in cryptic populations of the tunicate Lissoclinum patella. PLoS One. 2014 ;9(5):e95850.
. Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells. Genes Dev. 2016 ;30(15):1704-17.
. Identification of Sirtuin4 (SIRT4) Protein Interactions: Uncovering Candidate Acyl-Modified Mitochondrial Substrates and Enzymatic Regulators. Methods Mol Biol. 2016 ;1436:213-39.
. Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle. Cell Metab. 2016 ;24(2):269-82.
. Mitochondria and Cancer. Mol Cell. 2016 ;61(5):667-676.
. Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation. Cell Metab. 2016 ;24(1):104-17.
. Nanos-mediated repression of hid protects larval sensory neurons after a global switch in sensitivity to apoptotic signals. Development. 2016 ;143(12):2147-59.
. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metab. 2016 ;23(6):1140-1153.
. Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes. Sci Rep. 2017 ;7(1):12685.
. One-Carbon Metabolism in Health and Disease. Cell Metab. 2017 ;25(1):27-42.
. Traditional and novel tools to probe the mitochondrial metabolism in health and disease. Wiley Interdiscip Rev Syst Biol Med. 2017 ;9(2).
. Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice. Proc Natl Acad Sci U S A. 2018 ;115(52):13347-13352.
. Metabolomics and Isotope Tracing. Cell. 2018 ;173(4):822-837.
. Mitochondrial translation requires folate-dependent tRNA methylation. Nature. 2018 ;554(7690):128-132.
. The signature motif of the Saccharomyces cerevisiae Pif1 DNA helicase is essential in vivo for mitochondrial and nuclear functions and in vitro for ATPase activity. Nucleic Acids Res. 2018 ;46(16):8357-8370.
. Macrophage de novo NAD synthesis specifies immune function in aging and inflammation. Nat Immunol. 2019 ;20(1):50-63.
. Mitochondrial Function, Metabolic Regulation, and Human Disease Viewed through the Prism of Sirtuin 4 (SIRT4) Functions. J Proteome Res. 2019 ;18(5):1929-1938.
. Novel Pyrrolo[3,2-]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy. Mol Cancer Ther. 2019 ;18(10):1787-1799.
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Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Mol Cancer Res. 2020 ;18(4):599-611.
. Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria. Proc Natl Acad Sci U S A. 2020 ;117(42):26438-26447.
. Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA. Cell Rep. 2020 ;32(4):107943.
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