Search Publications
Export 28 results:
Author Title [ Year(Asc)]
Filters: Keyword is Mitochondria  [Clear All Filters]
Minhas PS, Latif-Hernandez A, McReynolds MR, Durairaj AS, Wang Q, Rubin A, et al. Restoring metabolism of myeloid cells reverses cognitive decline in ageing. Nature. 2021 ;590(7844):122-128.
Parkhitko AA, Ramesh D, Wang L, Leshchiner D, Filine E, Binari R, et al. Downregulation of the tyrosine degradation pathway extends lifespan. Elife. 2020 ;9.
Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, et al. Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Mol Cancer Res. 2020 ;18(4):599-611.
Mor DE, Sohrabi S, Kaletsky R, Keyes W, Tartici A, Kalia V, et al. Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria. Proc Natl Acad Sci U S A. 2020 ;117(42):26438-26447.
Federspiel JD, Cook KC, Kennedy MA, Venkatesh SS, Otter CJ, Hofstadter WA, et al. Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA. Cell Rep. 2020 ;32(4):107943.
Hammer SK, Zhang Y, Avalos JL. Mitochondrial Compartmentalization Confers Specificity to the 2-Ketoacid Recursive Pathway: Increasing Isopentanol Production in . ACS Synth Biol. 2020 ;9(3):546-555.
Luongo TS, Eller JM, Lu M-J, Niere M, Raith F, Perry C, et al. SLC25A51 is a mammalian mitochondrial NAD transporter. Nature. 2020 ;588(7836):174-179.
Minhas PS, Liu L, Moon PK, Joshi AU, Dove C, Mhatre S, et al. Macrophage de novo NAD synthesis specifies immune function in aging and inflammation. Nat Immunol. 2019 ;20(1):50-63.
Betsinger CN, Cristea IM. Mitochondrial Function, Metabolic Regulation, and Human Disease Viewed through the Prism of Sirtuin 4 (SIRT4) Functions. J Proteome Res. 2019 ;18(5):1929-1938.
Dekhne AS, Shah K, Ducker GS, Katinas JM, Wong-Roushar J, Nayeen MJunayed, et al. Novel Pyrrolo[3,2-]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy. Mol Cancer Ther. 2019 ;18(10):1787-1799.
Ron-Harel N, Notarangelo G, Ghergurovich JM, Paulo JA, Sage PT, Santos D, et al. Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice. Proc Natl Acad Sci U S A. 2018 ;115(52):13347-13352.
Jang C, Chen L, Rabinowitz JD. Metabolomics and Isotope Tracing. Cell. 2018 ;173(4):822-837.
Morscher RJ, Ducker GS, Li SHsin-Jung, Mayer JA, Gitai Z, Sperl W, et al. Mitochondrial translation requires folate-dependent tRNA methylation. Nature. 2018 ;554(7690):128-132.
Geronimo CL, Singh SP, Galletto R, Zakian VA. The signature motif of the Saccharomyces cerevisiae Pif1 DNA helicase is essential in vivo for mitochondrial and nuclear functions and in vitro for ATPase activity. Nucleic Acids Res. 2018 ;46(16):8357-8370.
Mirzaei M, Gupta VB, Chick JM, Greco TM, Wu Y, Chitranshi N, et al. Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes. Sci Rep. 2017 ;7(1):12685.
Ducker GS, Rabinowitz JD. One-Carbon Metabolism in Health and Disease. Cell Metab. 2017 ;25(1):27-42.
Zhang Y, Avalos JL. Traditional and novel tools to probe the mitochondrial metabolism in health and disease. Wiley Interdiscip Rev Syst Biol Med. 2017 ;9(2).
Guo JYanxiang, Teng X, Laddha SV, Ma S, Van Nostrand SC, Yang Y, et al. Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells. Genes Dev. 2016 ;30(15):1704-17.
Mathias RA, Greco TM, Cristea IM. Identification of Sirtuin4 (SIRT4) Protein Interactions: Uncovering Candidate Acyl-Modified Mitochondrial Substrates and Enzymatic Regulators. Methods Mol Biol. 2016 ;1436:213-39.
Frederick DW, Loro E, Liu L, Davila A, Chellappa K, Silverman IM, et al. Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle. Cell Metab. 2016 ;24(2):269-82.
Zong W-X, Rabinowitz JD, White E. Mitochondria and Cancer. Mol Cell. 2016 ;61(5):667-676.
Ron-Harel N, Santos D, Ghergurovich JM, Sage PT, Reddy A, Lovitch SB, et al. Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation. Cell Metab. 2016 ;24(1):104-17.
Bhogal B, Plaza-Jennings A, Gavis ER. Nanos-mediated repression of hid protects larval sensory neurons after a global switch in sensitivity to apoptotic signals. Development. 2016 ;143(12):2147-59.
Ducker GS, Chen L, Morscher RJ, Ghergurovich JM, Esposito M, Teng X, et al. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metab. 2016 ;23(6):1140-1153.
Kwan JC, Tianero MDiarey B, Donia MS, Wyche TP, Bugni TS, Schmidt EW. Host control of symbiont natural product chemistry in cryptic populations of the tunicate Lissoclinum patella. PLoS One. 2014 ;9(5):e95850.