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2022
Li X, Hui S, Mirek ET, Jonsson WO, Anthony TG, Lee WDong, et al. Circulating metabolite homeostasis achieved through mass action. Nat Metab. 2022 ;4(1):141-152.
Covington BC, Seyedsayamdost MR. Guidelines for metabolomics-guided transposon mutagenesis for microbial natural product discovery. Methods Enzymol. 2022 ;665:305-323.
Hansen J, Sealfon R, Menon R, Eadon MT, Lake BB, Steck B, et al. A reference tissue atlas for the human kidney. Sci Adv. 2022 ;8(23):eabn4965.
2021
Chen L, Lu W, Wang L, Xing X, Chen Z, Teng X, et al. Metabolite discovery through global annotation of untargeted metabolomics data. Nat Methods. 2021 ;18(11):1377-1385.
Covington BC, Seyedsayamdost MR. MetEx, a Metabolomics Explorer Application for Natural Product Discovery. ACS Chem Biol. 2021 ;16(12):2825-2833.
Bartman CR, TeSlaa T, Rabinowitz JD. Quantitative flux analysis in mammals. Nat Metab. 2021 ;3(7):896-908.
2020
Murashige D, Jang C, Neinast M, Edwards JJ, Cowan A, Hyman MC, et al. Comprehensive quantification of fuel use by the failing and nonfailing human heart. Science. 2020 ;370(6514):364-368.
Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, et al. Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Mol Cancer Res. 2020 ;18(4):599-611.
Farag MA, Hegazi NM, Donia MS. Molecular networking based LC/MS reveals novel biotransformation products of green coffee by ex vivo cultures of the human gut microbiome. Metabolomics. 2020 ;16(8):86.
Yoshimura A, Covington BC, Gallant É, Zhang C, Li A, Seyedsayamdost MR. Unlocking Cryptic Metabolites with Mass Spectrometry-Guided Transposon Mutant Selection. ACS Chem Biol. 2020 ;15(10):2766-2774.
2019
Tuttle RN, Demko AM, Patin NV, Kapono CA, Donia MS, Dorrestein P, et al. Detection of Natural Products and Their Producers in Ocean Sediments. Appl Environ Microbiol. 2019 ;85(8).
Xu F, Wu Y, Zhang C, Davis KM, Moon K, Bushin LB, et al. A genetics-free method for high-throughput discovery of cryptic microbial metabolites. Nat Chem Biol. 2019 ;15(2):161-168.
Dekhne AS, Shah K, Ducker GS, Katinas JM, Wong-Roushar J, Nayeen MJunayed, et al. Novel Pyrrolo[3,2-]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy. Mol Cancer Ther. 2019 ;18(10):1787-1799.
2018
Gong Y, Cao R, Ding G, Hong S, Zhou W, Lu W, et al. Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle. Mol Cell Endocrinol. 2018 ;471:22-32.
Jang C, Chen L, Rabinowitz JD. Metabolomics and Isotope Tracing. Cell. 2018 ;173(4):822-837.
2017
Kim HIn, Raffler J, Lu W, Lee J-J, Abbey D, Saleheen D, et al. Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport. Am J Hum Genet. 2017 ;101(4):489-502.
Lu W, Su X, Klein MS, Lewis IA, Fiehn O, Rabinowitz JD. Metabolite Measurement: Pitfalls to Avoid and Practices to Follow. Annu Rev Biochem. 2017 ;86:277-304.
Su X, Lu W, Rabinowitz JD. Metabolite Spectral Accuracy on Orbitraps. Anal Chem. 2017 ;89(11):5940-5948.
Beltran PMJean, Federspiel JD, Sheng X, Cristea IM. Proteomics and integrative omic approaches for understanding host-pathogen interactions and infectious diseases. Mol Syst Biol. 2017 ;13(3):922.
Zhang Y, Avalos JL. Traditional and novel tools to probe the mitochondrial metabolism in health and disease. Wiley Interdiscip Rev Syst Biol Med. 2017 ;9(2).
Rajeshkumar NV, Yabuuchi S, Pai SG, De Oliveira E, Kamphorst JJ, Rabinowitz JD, et al. Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin. Clin Cancer Res. 2017 ;23(18):5639-5647.
2016
Teng X, Emmett MJ, Lazar MA, Goldberg E, Rabinowitz JD. Lactate Dehydrogenase C Produces S-2-Hydroxyglutarate in Mouse Testis. ACS Chem Biol. 2016 ;11(9):2420-7.
Okada BK, Wu Y, Mao D, Bushin LB, Seyedsayamdost MR. Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis. ACS Chem Biol. 2016 ;11(8):2124-30.
Wilson MZ, Wang R, Gitai Z, Seyedsayamdost MR. Mode of action and resistance studies unveil new roles for tropodithietic acid as an anticancer agent and the γ-glutamyl cycle as a proton sink. Proc Natl Acad Sci U S A. 2016 ;113(6):1630-5.
Moloughney JG, Kim PK, Vega-Cotto NM, Wu C-C, Zhang S, Adlam M, et al. mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1. Mol Cell. 2016 ;63(5):811-26.