Publications
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Complex interplay between tumor microenvironment and cancer therapy. Front Med. 2018 ;12(4):426-439.
. Metastatic niche functions and therapeutic opportunities. Nat Cell Biol. 2018 ;20(8):868-877.
. Mitochondria and Cancer. Mol Cell. 2016 ;61(5):667-676.
. Mode of action and resistance studies unveil new roles for tropodithietic acid as an anticancer agent and the γ-glutamyl cycle as a proton sink. Proc Natl Acad Sci U S A. 2016 ;113(6):1630-5.
. molBLOCKS: decomposing small molecule sets and uncovering enriched fragments. Bioinformatics. 2014 ;30(14):2081-3.
. Novel Pyrrolo[3,2-]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy. Mol Cancer Ther. 2019 ;18(10):1787-1799.
. Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis. Oncogene. 2017 ;36(27):3797-3806.
. Recent advances and limitations in the application of kahalalides for the control of cancer. Biomed Pharmacother. 2022 ;148:112676.
. Stresses in the metastatic cascade: molecular mechanisms and therapeutic opportunities. Genes Dev. 2020 ;34(23-24):1577-1598.
. Telomerase RNA is more than a DNA template. RNA Biol. 2016 ;13(8):683-9.
. Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy. Cancer Cell. 2017 ;32(6):731-747.e6.
. Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin. Clin Cancer Res. 2017 ;23(18):5639-5647.
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