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2021
Balo AR, Caruso A, Tao L, Tantillo DJ, Seyedsayamdost MR, R Britt D. Trapping a cross-linked lysine-tryptophan radical in the catalytic cycle of the radical SAM enzyme SuiB. Proc Natl Acad Sci U S A. 2021 ;118(21).
2019
Minhas PS, Liu L, Moon PK, Joshi AU, Dove C, Mhatre S, et al. Macrophage de novo NAD synthesis specifies immune function in aging and inflammation. Nat Immunol. 2019 ;20(1):50-63.
Travis SM, Kokona B, Fairman R, Hughson FM. Roles of singleton tryptophan motifs in COPI coat stability and vesicle tethering. Proc Natl Acad Sci U S A. 2019 ;116(48):24031-24040.
Isley NA, Endo Y, Wu Z-C, Covington BC, Bushin LB, Seyedsayamdost MR, et al. Total Synthesis and Stereochemical Assignment of Streptide. J Am Chem Soc. 2019 ;141(43):17361-17369.
2018
Schramma KR, Forneris CC, Caruso A, Seyedsayamdost MR. Mechanistic Investigations of Lysine-Tryptophan Cross-Link Formation Catalyzed by Streptococcal Radical S-Adenosylmethionine Enzymes. Biochemistry. 2018 ;57(4):461-468.
Liu L, Su X, Quinn WJ, Hui S, Krukenberg K, Frederick DW, et al. Quantitative Analysis of NAD Synthesis-Breakdown Fluxes. Cell Metab. 2018 ;27(5):1067-1080.e5.
2017
Cervantes-Barragan L, Chai JN, Tianero MDiarey, Di Luccia B, Ahern PP, Merriman J, et al. induces gut intraepithelial CD4CD8αα T cells. Science. 2017 ;357(6353):806-810.
Schramma KR, Seyedsayamdost MR. Lysine-Tryptophan-Crosslinked Peptides Produced by Radical SAM Enzymes in Pathogenic Streptococci. ACS Chem Biol. 2017 ;12(4):922-927.
2015
Suckling RJ, Poon PPhi, Travis SM, Majoul IV, Hughson FM, Evans PR, et al. Structural basis for the binding of tryptophan-based motifs by δ-COP. Proc Natl Acad Sci U S A. 2015 ;112(46):14242-7.
Schramma KR, Bushin LB, Seyedsayamdost MR. Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink. Nat Chem. 2015 ;7(5):431-437.
2014
Williams BB, Van Benschoten AH, Cimermancic P, Donia MS, Zimmermann M, Taketani M, et al. Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine. Cell Host Microbe. 2014 ;16(4):495-503.