Publications
] . Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair. Nucleic Acids Res. 2021 ;49(4):2044-2064.
. Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells. Science. 2020 ;369(6502):397-403.
. Core components of DNA lagging strand synthesis machinery are essential for hepatitis B virus cccDNA formation. Nat Microbiol. 2020 ;5(5):715-726.
. Epithelial tissue geometry directs emergence of bioelectric field and pattern of proliferation. Mol Biol Cell. 2020 ;31(16):1691-1702.
. Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers. Cell. 2020 ;182(4):1044-1061.e18.
. Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA. Cell Rep. 2020 ;32(4):107943.
. Pseudorabies Virus Infection Accelerates Degradation of the Kinesin-3 Motor KIF1A. J Virol. 2020 ;94(9).
. A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating. mBio. 2020 ;11(2).
. SLC25A51 is a mammalian mitochondrial NAD transporter. Nature. 2020 ;588(7836):174-179.
. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Nat Chem Biol. 2020 ;16(7):731-739.
. Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2. Cell. 2020 ;182(1):98-111.e18.
. Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection. Nat Commun. 2020 ;11(1):806.
. TRANSPIRE: A Computational Pipeline to Elucidate Intracellular Protein Movements from Spatial Proteomics Data Sets. J Am Soc Mass Spectrom. 2020 ;31(7):1422-1439.
. BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila. Nat Commun. 2019 ;10(1):5700.
. Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus. Elife. 2019 ;8.
. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. 2019 ;567(7749):535-539.
. Investigating Mechanisms that Control Ubiquitin-Mediated DAF-16/FOXO Protein Turnover. Methods Mol Biol. 2019 ;1890:41-49.
. JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila. Nat Commun. 2019 ;10(1):5343.
. Near-equilibrium glycolysis supports metabolic homeostasis and energy yield. Nat Chem Biol. 2019 ;15(10):1001-1008.
. Nucleoporin insufficiency disrupts a pluripotent regulatory circuit in a pro-arrhythmogenic stem cell line. Sci Rep. 2019 ;9(1):12691.
. P2Y2 purinergic receptor modulates virus yield, calcium homeostasis, and cell motility in human cytomegalovirus-infected cells. Proc Natl Acad Sci U S A. 2019 ;116(38):18971-18982.
. Paip2 cooperates with Cbp80 at an active promoter and participates in RNA Polymerase II phosphorylation in Drosophila. FEBS Lett. 2019 ;593(10):1102-1112.
. Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity. Nat Immunol. 2019 ;20(8):1023-1034.
. PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor. Proc Natl Acad Sci U S A. 2019 ;116(44):22152-22157.
. Real-time 2-5A kinetics suggest that interferons β and λ evade global arrest of translation by RNase L. Proc Natl Acad Sci U S A. 2019 ;116(6):2103-2111.