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2022
Jack A, Kim Y, Strom AR, Lee DSW, Williams B, Schaub JM, et al. Compartmentalization of telomeres through DNA-scaffolded phase separation. Dev Cell. 2022 ;57(2):277-290.e9.
French H, Pitre E, Oade MS, Elshina E, Bisht K, King A, et al. Transient RNA structures cause aberrant influenza virus replication and innate immune activation. Sci Adv. 2022 ;8(36):eabp8655.
2021
Dai W, Li A, Yu NJ, Nguyen T, Leach RW, Wühr M, et al.. Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated dihydrouridylation. Nat Chem Biol. 2021 ;17(11):1178-1187.
Stahley SN, Basta LP, Sharan R, Devenport D. Celsr1 adhesive interactions mediate the asymmetric organization of planar polarity complexes. Elife. 2021 ;10.
Chen PJ, Hussmann JA, Yan J, Knipping F, Ravisankar P, Chen P-F, et al. Enhanced prime editing systems by manipulating cellular determinants of editing outcomes. Cell. 2021 ;184(22):5635-5652.e29.
Strom AR, Biggs RJ, Banigan EJ, Wang X, Chiu K, Herman C, et al. HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics. Elife. 2021 ;10.
Kilinc ANihan, Han S, Barrett LA, Anandasivam N, Nelson CM. Integrin-linked kinase tunes cell-cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ1. Mol Biol Cell. 2021 ;32(5):402-412.
Murray-Nerger LA, Justice JL, Rekapalli P, Hutton JE, Cristea IM. Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair. Nucleic Acids Res. 2021 ;49(4):2044-2064.
Hussmann JA, Ling J, Ravisankar P, Yan J, Cirincione A, Xu A, et al. Mapping the genetic landscape of DNA double-strand break repair. Cell. 2021 ;184(22):5653-5669.e25.
Shim G, Devenport D, Cohen DJ. Overriding native cell coordination enhances external programming of collective cell migration. Proc Natl Acad Sci U S A. 2021 ;118(29).
Sochacki KA, Heine BL, Haber GJ, Jimah JR, Prasai B, Alfonzo-Méndez MA, et al.. The structure and spontaneous curvature of clathrin lattices at the plasma membrane. Dev Cell. 2021 ;56(8):1131-1146.e3.
2020
Xu Y, Zhang Y, García-Cañaveras JC, Guo L, Kan M, Yu S, et al.. Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells. Science. 2020 ;369(6502):397-403.
Wei L, Ploss A. Core components of DNA lagging strand synthesis machinery are essential for hepatitis B virus cccDNA formation. Nat Microbiol. 2020 ;5(5):715-726.
Silver BB, Wolf AE, Lee J, Pang M-F, Nelson CM. Epithelial tissue geometry directs emergence of bioelectric field and pattern of proliferation. Mol Biol Cell. 2020 ;31(16):1691-1702.
Hoshino A, Kim HSang, Bojmar L, Gyan KEnnu, Cioffi M, Hernandez J, et al. Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers. Cell. 2020 ;182(4):1044-1061.e18.
Federspiel JD, Cook KC, Kennedy MA, Venkatesh SS, Otter CJ, Hofstadter WA, et al. Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA. Cell Rep. 2020 ;32(4):107943.
Huang H, Koyuncu OO, Enquist LW. Pseudorabies Virus Infection Accelerates Degradation of the Kinesin-3 Motor KIF1A. J Virol. 2020 ;94(9).
Ramanathan HN, Zhang S, Douam F, Mar KB, Chang J, Yang PL, et al. A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating. mBio. 2020 ;11(2).
Yang L, Canaveras JCarlos Gar, Chen Z, Wang L, Liang L, Jang C, et al. Serine Catabolism Feeds NADH when Respiration Is Impaired. Cell Metab. 2020 ;31(4):809-821.e6.
Luongo TS, Eller JM, Lu M-J, Niere M, Raith F, Perry C, et al. SLC25A51 is a mammalian mitochondrial NAD transporter. Nature. 2020 ;588(7836):174-179.
Ghergurovich JM, García-Cañaveras JC, Wang J, Schmidt E, Zhang Z, TeSlaa T, et al.. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Nat Chem Biol. 2020 ;16(7):731-739.
Qian H, Wu X, Du X, Yao X, Zhao X, Lee J, et al. Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2. Cell. 2020 ;182(1):98-111.e18.
Hashimoto Y, Sheng X, Murray-Nerger LA, Cristea IM. Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection. Nat Commun. 2020 ;11(1):806.
Kennedy MA, Hofstadter WA, Cristea IM. TRANSPIRE: A Computational Pipeline to Elucidate Intracellular Protein Movements from Spatial Proteomics Data Sets. J Am Soc Mass Spectrom. 2020 ;31(7):1422-1439.
2019
Ueberschär M, Wang H, Zhang C, Kondo S, Aoki T, Schedl P, et al.. BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila. Nat Commun. 2019 ;10(1):5700.