Publications
Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer. Nat Cancer. 2022 ;3(1):60-74.
. Structure-Based Design, Optimization, and Evaluation of Potent Stabilized Peptide Inhibitors Disrupting MTDH and SND1 Interaction. J Med Chem. 2022 ;65(18):12188-12199.
. Bone marrow niches in the regulation of bone metastasis. Br J Cancer. 2021 ;124(12):1912-1920.
. Dll1 quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway. Nat Commun. 2021 ;12(1):432.
. Evolving barcodes shed light into evolving metastases. Dev Cell. 2021 ;56(8):1077-1079.
. Matrix degradation and cell proliferation are coupled to promote invasion and escape from an engineered human breast microtumor. Integr Biol (Camb). 2021 ;13(1):17-29.
. Substratum stiffness signals through integrin-linked kinase and β1-integrin to regulate midbody proteins and abscission during EMT. Mol Biol Cell. 2021 ;32(18):1664-1676.
. TGF-β-induced DACT1 biomolecular condensates repress Wnt signalling to promote bone metastasis. Nat Cell Biol. 2021 ;23(3):257-267.
. . ASB13 inhibits breast cancer metastasis through promoting SNAI2 degradation and relieving its transcriptional repression of YAP. Genes Dev. 2020 ;34(19-20):1359-1372.
. Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2. Genes Dev. 2020 ;34(19-20):1310-1315.
. Differential Allele-Specific Expression Uncovers Breast Cancer Genes Dysregulated by Cis Noncoding Mutations. Cell Syst. 2020 ;10(2):193-203.e4.
. E-cigarette promotes breast carcinoma progression and lung metastasis: Macrophage-tumor cells crosstalk and the role of CCL5 and VCAM-1. Cancer Lett. 2020 ;491:132-145.
. HSATII RNA is induced via a noncanonical ATM-regulated DNA damage response pathway and promotes tumor cell proliferation and movement. Proc Natl Acad Sci U S A. 2020 ;117(50):31891-31901.
. Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Mol Cancer Res. 2020 ;18(4):599-611.
. Soft Microenvironments Induce Chemoresistance by Increasing Autophagy Downstream of Integrin-Linked Kinase. Cancer Res. 2020 ;80(19):4103-4113.
. Subtype-specific transcriptional regulators in breast tumors subjected to genetic and epigenetic alterations. Bioinformatics. 2020 ;36(4):994-999.
. A biomimetic 3D model of hypoxia-driven cancer progression. Sci Rep. 2019 ;9(1):12263.
. CD44 splice isoform switching determines breast cancer stem cell state. Genes Dev. 2019 ;33(3-4):166-179.
. Role Reversal: A Pro-metastatic Function of E-Cadherin. Dev Cell. 2019 ;51(4):417-419.
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Identification of Nidogen 1 as a lung metastasis protein through secretome analysis. Genes Dev. 2017 ;31(14):1439-1455.
. Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a-LCOR axis. Nat Cell Biol. 2017 ;19(6):711-723.
. Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis. Oncogene. 2017 ;36(27):3797-3806.
. Short-term and long-term clinical outcomes of uncommon types of invasive breast cancer. Histopathology. 2017 ;71(6):874-886.
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