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Filters: Keyword is Endoribonucleases [Clear All Filters]
Concerted 2-5A-Mediated mRNA Decay and Transcription Reprogram Protein Synthesis in the dsRNA Response. Mol Cell. 2019 ;75(6):1218-1228.e6..
Innate immune messenger 2-5A tethers human RNase L into active high-order complexes. Cell Rep. 2012 ;2(4):902-13..
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 ;167(7):1867-1882.e21..
Real-time 2-5A kinetics suggest that interferons β and λ evade global arrest of translation by RNase L. Proc Natl Acad Sci U S A. 2019 ;116(6):2103-2111..
Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line. Elife. 2017 ;6..
RNA Futile Cycling in Model Persisters Derived from MazF Accumulation. mBio. 2015 ;6(6):e01588-15..
Structural basis of the unfolded protein response. Annu Rev Cell Dev Biol. 2012 ;28:251-77..
Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3. Proc Natl Acad Sci U S A. 2015 ;112(13):3949-54..
Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response. Science. 2014 ;343(6176):1244-8..
Timing of DNA damage responses impacts persistence to fluoroquinolones. Proc Natl Acad Sci U S A. 2018 ;115(27):E6301-E6309..