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2022
Hansen J, Sealfon R, Menon R, Eadon MT, Lake BB, Steck B, et al. A reference tissue atlas for the human kidney. Sci Adv. 2022 ;8(23):eabn4965.
Zhang Z, Zamojski M, Smith GR, Willis TL, Yianni V, Mendelev N, et al. Single nucleus transcriptome and chromatin accessibility of postmortem human pituitaries reveal diverse stem cell regulatory mechanisms. Cell Rep. 2022 ;38(10):110467.
Chen X, Du Y, Broussard GJoey, Kislin M, Yuede CM, Zhang S, et al. Transcriptomic mapping uncovers Purkinje neuron plasticity driving learning. Nature. 2022 ;605(7911):722-727.
2021
Kleiner RE. Interrogating the transcriptome with metabolically incorporated ribonucleosides. Mol Omics. 2021 ;17(6):833-841.
Ruf-Zamojski F, Zhang Z, Zamojski M, Smith GR, Mendelev N, Liu H, et al. Single nucleus multi-omics regulatory landscape of the murine pituitary. Nat Commun. 2021 ;12(1):2677.
Quinn JJ, Jones MG, Okimoto RA, Nanjo S, Chan MM, Yosef N, et al. Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts. Science. 2021 ;371(6532).
Lindström NO, Sealfon R, Chen X, Parvez RK, Ransick A, Brandine GDe Sena, et al.. Spatial transcriptional mapping of the human nephrogenic program. Dev Cell. 2021 ;56(16):2381-2398.e6.
Goodwin K, Nelson CM. Uncovering cellular networks in branching morphogenesis using single-cell transcriptomics. Curr Top Dev Biol. 2021 ;143:239-280.
2020
Replogle JM, Norman TM, Xu A, Hussmann JA, Chen J, J Cogan Z, et al. Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing. Nat Biotechnol. 2020 ;38(8):954-961.
Ledo JHenrique, Zhang R, Mesin L, Mourão-Sá D, Azevedo EP, Troyanskaya OG, et al.. Lack of a site-specific phosphorylation of Presenilin 1 disrupts microglial gene networks and progenitors during development. PLoS One. 2020 ;15(8):e0237773.
Cao WXi, Kabelitz S, Gupta M, Yeung E, Lin S, Rammelt C, et al. Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cell Rep. 2020 ;31(12):107783.
Roussarie J-P, Yao V, Rodriguez-Rodriguez P, Oughtred R, Rust J, Plautz Z, et al. Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis. Neuron. 2020 ;107(5):821-835.e12.
2019
Zhou J, Schor IE, Yao V, Theesfeld CL, Marco-Ferreres R, Tadych A, et al. Accurate genome-wide predictions of spatio-temporal gene expression during embryonic development. PLoS Genet. 2019 ;15(9):e1008382.
Lee Y-S, Krishnan A, Oughtred R, Rust J, Chang CS, Ryu J, et al. A Computational Framework for Genome-wide Characterization of the Human Disease Landscape. Cell Syst. 2019 ;8(2):152-162.e6.
Federspiel JD, Greco TM, Lum KK, Cristea IM. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Mol Cell Proteomics. 2019 ;18(8 suppl 1):S92-S113.
Sanfilippo JE, Lorestani A, Koch MD, Bratton BP, Siryaporn A, Stone HA, et al. Microfluidic-based transcriptomics reveal force-independent bacterial rheosensing. Nat Microbiol. 2019 ;4(8):1274-1281.
Arey RN, Kaletsky R, Murphy CT. Nervous system-wide profiling of presynaptic mRNAs reveals regulators of associative memory. Sci Rep. 2019 ;9(1):20314.
Preston CC, Storm EC, Burdine RD, Bradley TA, Uttecht AD, Faustino RS. Nucleoporin insufficiency disrupts a pluripotent regulatory circuit in a pro-arrhythmogenic stem cell line. Sci Rep. 2019 ;9(1):12691.
Harder JL, Menon R, Otto EA, Zhou J, Eddy S, Wys NL, et al. Organoid single cell profiling identifies a transcriptional signature of glomerular disease. JCI Insight. 2019 ;4(1).
2018
vonHoldt BM, Ji SS, Aardema ML, Stahler DR, Udell MAR, Sinsheimer JS. Activity of Genes with Functions in Human Williams-Beuren Syndrome Is Impacted by Mobile Element Insertions in the Gray Wolf Genome. Genome Biol Evol. 2018 ;10(6):1546-1553.
Templeman NM, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, et al. Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity. Curr Biol. 2018 ;28(5):753-760.e4.
Gong Y, Cao R, Ding G, Hong S, Zhou W, Lu W, et al. Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle. Mol Cell Endocrinol. 2018 ;471:22-32.
Douam F, Ziegler CGK, Hrebikova G, Fant B, Leach R, Parsons L, et al. Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses. Nat Commun. 2018 ;9(1):5031.
2017
Wilson MZ, Ravindran PT, Lim WA, Toettcher JE. Tracing Information Flow from Erk to Target Gene Induction Reveals Mechanisms of Dynamic and Combinatorial Control. Mol Cell. 2017 ;67(5):757-769.e5.
Tate AT, Andolfatto P, Demuth JP, Graham AL. The within-host dynamics of infection in trans-generationally primed flour beetles. Mol Ecol. 2017 ;26(14):3794-3807.