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2020
Vrla GD, Esposito M, Zhang C, Kang Y, Seyedsayamdost MR, Gitai Z. Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa. PLoS Pathog. 2020 ;16(9):e1008867.
Grimes DT, Patterson VL, Luna-Arvizu G, Schottenfeld-Roames J, Irons ZH, Burdine RD. Left-right asymmetric heart jogging increases the robustness of dextral heart looping in zebrafish. Dev Biol. 2020 ;459(2):79-86.
Huang X, Duddy OP, Silpe JE, Paczkowski JE, Cong J, Henke BR, et al. Mechanism underlying autoinducer recognition in the DPO-VqmA quorum-sensing pathway. J Biol Chem. 2020 ;295(10):2916-2931.
Gil AA, Carrasco-López C, Zhu L, Zhao EM, Ravindran PT, Wilson MZ, et al.. Optogenetic control of protein binding using light-switchable nanobodies. Nat Commun. 2020 ;11(1):4044.
Heimbucher T, Hog J, Gupta P, Murphy CT. PQM-1 controls hypoxic survival via regulation of lipid metabolism. Nat Commun. 2020 ;11(1):4627.
Hashimoto Y, Sheng X, Murray-Nerger LA, Cristea IM. Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection. Nat Commun. 2020 ;11(1):806.
2019
Monsivais D, Peng J, Kang Y, Matzuk MM. Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma. Proc Natl Acad Sci U S A. 2019 ;116(9):3883-3892.
Paczkowski JE, McCready AR, Cong J-P, Li Z, Jeffrey PD, Smith CD, et al. An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. ACS Chem Biol. 2019 ;14(3):378-389.
Esposito M, Mondal N, Greco TM, Wei Y, Spadazzi C, Lin S-C, et al. Bone vascular niche E-selectin induces mesenchymal-epithelial transition and Wnt activation in cancer cells to promote bone metastasis. Nat Cell Biol. 2019 ;21(5):627-639.
Goglia AG, Toettcher JE. A bright future: optogenetics to dissect the spatiotemporal control of cell behavior. Curr Opin Chem Biol. 2019 ;48:106-113.
Zhang H, Brown RL, Wei Y, Zhao P, Liu S, Liu X, et al. CD44 splice isoform switching determines breast cancer stem cell state. Genes Dev. 2019 ;33(3-4):166-179.
Hall AE, Rose MD. Cell fusion in yeast is negatively regulated by components of the cell wall integrity pathway. Mol Biol Cell. 2019 ;30(4):441-452.
Barr J, Charania S, Gilmutdinov R, Yakovlev K, Shidlovskii, ii Y, Schedl P. The CPEB translational regulator, Orb, functions together with Par proteins to polarize the Drosophila oocyte. PLoS Genet. 2019 ;15(3):e1008012.
Mesev EV, LeDesma RA, Ploss A. Decoding type I and III interferon signalling during viral infection. Nat Microbiol. 2019 ;4(6):914-924.
Hart EM, O'Connell A, Tang K, Wzorek JS, Grabowicz M, Kahne D, et al. Fine-Tuning of σ Activation Suppresses Multiple Assembly-Defective Mutations in Escherichia coli. J Bacteriol. 2019 ;201(11).
Bialistoky T, Manry D, Smith P, Ng C, Kim Y, Zamir S, et al. Functional analysis of Niemann-Pick disease type C family protein, NPC1a, in . Development. 2019 ;146(10).
Wittes J, Schüpbach T. A Gene Expression Screen in Identifies Novel JAK/STAT and EGFR Targets During Oogenesis. G3 (Bethesda). 2019 ;9(1):47-60.
Xie Q, Zhao A, Jeffrey PD, Kim MKevin, Bassler BL, Stone HA, et al. Identification of a Molecular Latch that Regulates Staphylococcal Virulence. Cell Chem Biol. 2019 ;26(4):548-558.e4.
Shi C, Booth LN, Murphy CT. Insulin-like peptides and the mTOR-TFEB pathway protect hermaphrodites from mating-induced death. Elife. 2019 ;8.
Bridges AA, Bassler BL. The intragenus and interspecies quorum-sensing autoinducers exert distinct control over Vibrio cholerae biofilm formation and dispersal. PLoS Biol. 2019 ;17(11):e3000429.
Minhas PS, Liu L, Moon PK, Joshi AU, Dove C, Mhatre S, et al. Macrophage de novo NAD synthesis specifies immune function in aging and inflammation. Nat Immunol. 2019 ;20(1):50-63.
Hashimoto Y, Kinoshita N, Greco TM, Federspiel JD, Beltran PMJean, Ueno N, et al. Mechanical Force Induces Phosphorylation-Mediated Signaling that Underlies Tissue Response and Robustness in Xenopus Embryos. Cell Syst. 2019 ;8(3):226-241.e7.
Chen S, Shenk T, Nogalski MT. P2Y2 purinergic receptor modulates virus yield, calcium homeostasis, and cell motility in human cytomegalovirus-infected cells. Proc Natl Acad Sci U S A. 2019 ;116(38):18971-18982.
Goodwin K, Mao S, Guyomar T, Miller E, Radisky DC, Košmrlj A, et al.. Smooth muscle differentiation shapes domain branches during mouse lung development. Development. 2019 ;146(22).
Shen M, Jiang Y-Z, Wei Y, Ell B, Sheng X, Esposito M, et al. Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling. Cancer Cell. 2019 ;35(1):64-80.e7.