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2020
Dao HT, Dul BE, Dann GP, Liszczak GP, Muir TW. A basic motif anchoring ISWI to nucleosome acidic patch regulates nucleosome spacing. Nat Chem Biol. 2020 ;16(2):134-142.
Nechay M, Kleiner RE. High-throughput approaches to profile RNA-protein interactions. Curr Opin Chem Biol. 2020 ;54:37-44.
Wetzel JL, Singh M. Sharing DNA-binding information across structurally similar proteins enables accurate specificity determination. Nucleic Acids Res. 2020 ;48(2):e9.
Wang L, Qian H, Nian Y, Han Y, Ren Z, Zhang H, et al. Structure and mechanism of human diacylglycerol O-acyltransferase 1. Nature. 2020 ;581(7808):329-332.
2019
Zhao Y, Huang G, Wu Q, Wu K, Li R, Lei J, et al. Cryo-EM structures of apo and antagonist-bound human Ca3.1. Nature. 2019 ;576(7787):492-497.
Saunders JT, Schwarzbauer JE. Fibronectin matrix as a scaffold for procollagen proteinase binding and collagen processing. Mol Biol Cell. 2019 ;30(17):2218-2226.
Fedotova A, Clendinen C, Bonchuk A, Mogila V, Aoki T, Georgiev P, et al. Functional dissection of the developmentally restricted BEN domain chromatin boundary factor Insensitive. Epigenetics Chromatin. 2019 ;12(1):2.
Jani KS, Jain SU, Ge EJ, Diehl KL, Lundgren SM, Müller MM, et al.. Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase. Proc Natl Acad Sci U S A. 2019 ;116(17):8295-8300.
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, et al. Modulation of cardiac ryanodine receptor 2 by calmodulin. Nature. 2019 ;572(7769):347-351.
Zhao Y, Huang G, Wu J, Wu Q, Gao S, Yan Z, et al. Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca2+ Channel. Cell. 2019 ;177(6):1495-1506.e12.
Diehl KL, Ge EJ, Weinberg DN, Jani KS, C Allis D, Muir TW. PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor. Proc Natl Acad Sci U S A. 2019 ;116(44):22152-22157.
Shen H, Liu D, Wu K, Lei J, Yan N. Structures of human Na1.7 channel in complex with auxiliary subunits and animal toxins. Science. 2019 ;363(6433):1303-1308.
Kobren SNadimpalli, Singh M. Systematic domain-based aggregation of protein structures highlights DNA-, RNA- and other ligand-binding positions. Nucleic Acids Res. 2019 ;47(2):582-593.
2018
Wojcik F, Dann GP, Beh LY, Debelouchina GT, Hofmann R, Muir TW. Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants. Nat Commun. 2018 ;9(1):1394.
Raitman I, Huang ML, Williams SA, Friedman B, Godula K, Schwarzbauer JE. Heparin-fibronectin interactions in the development of extracellular matrix insolubility. Matrix Biol. 2018 ;67:107-122.
Gong X, Qian H, Cao P, Zhao X, Zhou Q, Lei J, et al. Structural basis for the recognition of Sonic Hedgehog by human Patched1. Science. 2018 ;361(6402).
Munro D, Ghersi D, Singh M. Two critical positions in zinc finger domains are heavily mutated in three human cancer types. PLoS Comput Biol. 2018 ;14(6):e1006290.
2017
Liszczak GP, Brown ZZ, Kim SH, Oslund RC, David Y, Muir TW. Genomic targeting of epigenetic probes using a chemically tailored Cas9 system. Proc Natl Acad Sci U S A. 2017 ;114(4):681-686.
Crow MS, Cristea IM. Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation. Mol Cell Proteomics. 2017 ;16(4 suppl 1):S200-S214.
Ducker GS, Ghergurovich JM, Mainolfi N, Suri V, Jeong SK, Li SHsin-Jung, et al. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A. 2017 ;114(43):11404-11409.
2016
Frutos S, Jordan JB, Bio MM, Muir TW, Thiel OR, Vila-Perelló M. Access to site-specific Fc-cRGD peptide conjugates through streamlined expressed protein ligation. Org Biomol Chem. 2016 ;14(40):9549-9553.
Jaffe KM, Grimes DT, Schottenfeld-Roames J, Werner ME, Ku T-SJ, Kim SK, et al. c21orf59/kurly Controls Both Cilia Motility and Polarization. Cell Rep. 2016 ;14(8):1841-9.
Jiang X, Smirnova I, Kasho V, Wu J, Hirata K, Ke M, et al. Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation. Proc Natl Acad Sci U S A. 2016 ;113(44):12420-12425.
Blythe SA, Wieschaus EF. Establishment and maintenance of heritable chromatin structure during early embryogenesis. Elife. 2016 ;5.
Kyrchanova O, Mogila V, Wolle D, Deshpande G, Parshikov A, Cleard F, et al. Functional Dissection of the Blocking and Bypass Activities of the Fab-8 Boundary in the Drosophila Bithorax Complex. PLoS Genet. 2016 ;12(7):e1006188.