Publications
] . Core components of DNA lagging strand synthesis machinery are essential for hepatitis B virus cccDNA formation. Nat Microbiol. 2020 ;5(5):715-726.
. Master of Disguise: Hepatitis Delta Virus Packaging and Spread Facilitated by Diverse Viral Envelope Proteins. Hepatology. 2020 ;71(1):380-382.
. RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters. PLoS Pathog. 2020 ;16(2):e1008269.
. Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection. Nat Commun. 2020 ;11(1):806.
. Alphaherpesvirus infection of mice primes PNS neurons to an inflammatory state regulated by TLR2 and type I IFN signaling. PLoS Pathog. 2019 ;15(11):e1008087.
. Charge-Mediated Pyrin Oligomerization Nucleates Antiviral IFI16 Sensing of Herpesvirus DNA. mBio. 2019 ;10(4).
. Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus. Elife. 2019 ;8.
. Location is everything: protein translocations as a viral infection strategy. Curr Opin Chem Biol. 2019 ;48:34-43.
. P2Y2 purinergic receptor modulates virus yield, calcium homeostasis, and cell motility in human cytomegalovirus-infected cells. Proc Natl Acad Sci U S A. 2019 ;116(38):18971-18982.
. Peroxisome Plasticity at the Virus-Host Interface. Trends Microbiol. 2019 ;27(11):906-914.
. Functional Carboxy-Terminal Fluorescent Protein Fusion to Pseudorabies Virus Small Capsid Protein VP26. J Virol. 2018 ;92(1).
. Infection-Induced Peroxisome Biogenesis Is a Metabolic Strategy for Herpesvirus Replication. Cell Host Microbe. 2018 ;24(4):526-541.e7.
. Interpretation of an individual functional genomics experiment guided by massive public data. Nat Methods. 2018 ;15(12):1049-1052.
. Orchestration of protein acetylation as a toggle for cellular defense and virus replication. Nat Commun. 2018 ;9(1):4967.
. A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism. PLoS Pathog. 2018 ;14(3):e1006908.
. Compartmented neuronal cultures reveal two distinct mechanisms for alpha herpesvirus escape from genome silencing. PLoS Pathog. 2017 ;13(10):e1006608.
. Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles. Proc Natl Acad Sci U S A. 2017 ;114(5):1147-1152.
. Normal human cell proteins that interact with the adenovirus type 5 E1B 55kDa protein. Virology. 2017 ;504:12-24.
. Recapitulation of treatment response patterns in a novel humanized mouse model for chronic hepatitis B virus infection. Virology. 2017 ;502:63-72.
. Selection of the highly replicative and partially multidrug resistant rtS78T HBV polymerase mutation during TDF-ETV combination therapy. J Hepatol. 2017 ;67(2):246-254.
. Diverse mechanisms evolved by DNA viruses to inhibit early host defenses. Crit Rev Biochem Mol Biol. 2016 ;51(6):452-481.
. Identification of RNA Binding Proteins Associated with Dengue Virus RNA in Infected Cells Reveals Temporally Distinct Host Factor Requirements. PLoS Negl Trop Dis. 2016 ;10(8):e0004921.
. A Portrait of the Human Organelle Proteome In Space and Time during Cytomegalovirus Infection. Cell Syst. 2016 ;3(4):361-373.e6.
. DNA methyltransferase DNMT3A associates with viral proteins and impacts HSV-1 infection. Proteomics. 2015 ;15(12):1968-82.