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Hart EM, Gupta M, Wühr M, Silhavy TJ. The Synthetic Phenotype of Δ Δ Double Mutants Results from a Lethal Jamming of the Bam Complex by the Lipoprotein RcsF. mBio. 2019 ;10(3).
Konovalova A, Schwalm JA, Silhavy TJ. A Suppressor Mutation That Creates a Faster and More Robust σE Envelope Stress Response. J Bacteriol. 2016 ;198(17):2345-51.
Lee J, Sutterlin HA, Wzorek JS, Mandler MD, Hagan CL, Grabowicz M, et al. Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion. Proc Natl Acad Sci U S A. 2018 ;115(10):2359-2364.
Hart EM, Mitchell AM, Konovalova A, Grabowicz M, Sheng J, Han X, et al. A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier. Proc Natl Acad Sci U S A. 2019 ;116(43):21748-21757.
Combs AN, Silhavy TJ. The sacrificial adaptor protein Skp functions to remove stalled substrates from the β-barrel assembly machine. Proc Natl Acad Sci U S A. 2022 ;119(1).
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Grabowicz M, Silhavy TJ. Redefining the essential trafficking pathway for outer membrane lipoproteins. Proc Natl Acad Sci U S A. 2017 ;114(18):4769-4774.
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Sun J, Rutherford ST, Silhavy TJ, Huang KCasey. Physical properties of the bacterial outer membrane. Nat Rev Microbiol. 2022 ;20(4):236-248.
May KL, Silhavy TJ. The Phospholipase PldA Regulates Outer Membrane Homeostasis via Lipid Signaling. mBio. 2018 ;9(2).
Benn G, Mikheyeva IV, Inns PGeorge, Forster JC, Ojkic N, Bortolini C, et al. Phase separation in the outer membrane of . Proc Natl Acad Sci U S A. 2021 ;118(44).
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Ricci DP, Silhavy TJ. Outer Membrane Protein Insertion by the β-barrel Assembly Machine. EcoSal Plus. 2019 ;8(2).
Konovalova A, Silhavy TJ. Outer membrane lipoprotein biogenesis: Lol is not the end. Philos Trans R Soc Lond B Biol Sci. 2015 ;370(1679).
Konovalova A, Kahne DE, Silhavy TJ. Outer Membrane Biogenesis. Annu Rev Microbiol. 2017 ;71:539-556.
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Konovalova A, Mitchell AM, Silhavy TJ. A lipoprotein/β-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane. Elife. 2016 ;5.
Okuda S, Sherman DJ, Silhavy TJ, Ruiz N, Kahne D. Lipopolysaccharide transport and assembly at the outer membrane: the PEZ model. Nat Rev Microbiol. 2016 ;14(6):337-45.
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Sacco SA, Adolfsen KJ, Brynildsen MP. An integrated network analysis identifies how ArcAB enables metabolic oscillations in the nitric oxide detoxification network of Escherichia coli. Biotechnol J. 2017 ;12(8).
Konovalova A, Grabowicz M, Balibar CJ, Malinverni JC, Painter RE, Riley D, et al. Inhibitor of intramembrane protease RseP blocks the σ response causing lethal accumulation of unfolded outer membrane proteins. Proc Natl Acad Sci U S A. 2018 ;115(28):E6614-E6621.
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Hart EM, Gupta M, Wühr M, Silhavy TJ. The gain-of-function allele bypasses the essential requirement for BamD in β-barrel outer membrane protein assembly. Proc Natl Acad Sci U S A. 2020 ;117(31):18737-18743.
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Hart EM, Silhavy TJ. Functions of the BamBCDE Lipoproteins Revealed by Bypass Mutations in BamA. J Bacteriol. 2020 ;202(21).
Hart EM, O'Connell A, Tang K, Wzorek JS, Grabowicz M, Kahne D, et al. Fine-Tuning of σ Activation Suppresses Multiple Assembly-Defective Mutations in Escherichia coli. J Bacteriol. 2019 ;201(11).
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Grabowicz M, Yeh J, Silhavy TJ. Dominant negative lptE mutation that supports a role for LptE as a plug in the LptD barrel. J Bacteriol. 2013 ;195(6):1327-34.
Soltes GR, Martin NR, Park E, Sutterlin HA, Silhavy TJ. Distinctive Roles for Periplasmic Proteases in the Maintenance of Essential Outer Membrane Protein Assembly. J Bacteriol. 2017 ;199(20).
Taylor JA, Bratton BP, Sichel SR, Blair KM, Jacobs HM, DeMeester KE, et al. Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in . Elife. 2020 ;9.
Sutterlin HA, Shi H, May KL, Miguel A, Khare S, Huang KCasey, et al. Disruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway. Proc Natl Acad Sci U S A. 2016 ;113(11):E1565-74.