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2019
Hart EM, O'Connell A, Tang K, Wzorek JS, Grabowicz M, Kahne D, et al. Fine-Tuning of σ Activation Suppresses Multiple Assembly-Defective Mutations in Escherichia coli. J Bacteriol. 2019 ;201(11).
Ricci DP, Silhavy TJ. Outer Membrane Protein Insertion by the β-barrel Assembly Machine. EcoSal Plus. 2019 ;8(2).
Hart EM, Mitchell AM, Konovalova A, Grabowicz M, Sheng J, Han X, et al. A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier. Proc Natl Acad Sci U S A. 2019 ;116(43):21748-21757.
Hart EM, Gupta M, Wühr M, Silhavy TJ. The Synthetic Phenotype of Δ Δ Double Mutants Results from a Lethal Jamming of the Bam Complex by the Lipoprotein RcsF. mBio. 2019 ;10(3).
2018
Mitchell AM, Srikumar T, Silhavy TJ. Cyclic Enterobacterial Common Antigen Maintains the Outer Membrane Permeability Barrier of Escherichia coli in a Manner Controlled by YhdP. mBio. 2018 ;9(4).
Konovalova A, Grabowicz M, Balibar CJ, Malinverni JC, Painter RE, Riley D, et al. Inhibitor of intramembrane protease RseP blocks the σ response causing lethal accumulation of unfolded outer membrane proteins. Proc Natl Acad Sci U S A. 2018 ;115(28):E6614-E6621.
May KL, Silhavy TJ. The Phospholipase PldA Regulates Outer Membrane Homeostasis via Lipid Signaling. mBio. 2018 ;9(2).
Lee J, Sutterlin HA, Wzorek JS, Mandler MD, Hagan CL, Grabowicz M, et al. Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion. Proc Natl Acad Sci U S A. 2018 ;115(10):2359-2364.
2017
McCabe AL, Ricci D, Adetunji M, Silhavy TJ. Conformational Changes That Coordinate the Activity of BamA and BamD Allowing β-Barrel Assembly. J Bacteriol. 2017 ;199(20).
Soltes GR, Martin NR, Park E, Sutterlin HA, Silhavy TJ. Distinctive Roles for Periplasmic Proteases in the Maintenance of Essential Outer Membrane Protein Assembly. J Bacteriol. 2017 ;199(20).
Sacco SA, Adolfsen KJ, Brynildsen MP. An integrated network analysis identifies how ArcAB enables metabolic oscillations in the nitric oxide detoxification network of Escherichia coli. Biotechnol J. 2017 ;12(8).
Konovalova A, Kahne DE, Silhavy TJ. Outer Membrane Biogenesis. Annu Rev Microbiol. 2017 ;71:539-556.
Grabowicz M, Silhavy TJ. Redefining the essential trafficking pathway for outer membrane lipoproteins. Proc Natl Acad Sci U S A. 2017 ;114(18):4769-4774.
2016
Soltes GR, Schwalm J, Ricci DP, Silhavy TJ. The Activity of Escherichia coli Chaperone SurA Is Regulated by Conformational Changes Involving a Parvulin Domain. J Bacteriol. 2016 ;198(6):921-9.
Lee J, Xue M, Wzorek JS, Wu T, Grabowicz M, Gronenberg LS, et al. Characterization of a stalled complex on the β-barrel assembly machine. Proc Natl Acad Sci U S A. 2016 ;113(31):8717-22.
Mahoney TF, Ricci DP, Silhavy TJ. Classifying β-Barrel Assembly Substrates by Manipulating Essential Bam Complex Members. J Bacteriol. 2016 ;198(14):1984-92.
Sutterlin HA, Shi H, May KL, Miguel A, Khare S, Huang KCasey, et al. Disruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway. Proc Natl Acad Sci U S A. 2016 ;113(11):E1565-74.
Okuda S, Sherman DJ, Silhavy TJ, Ruiz N, Kahne D. Lipopolysaccharide transport and assembly at the outer membrane: the PEZ model. Nat Rev Microbiol. 2016 ;14(6):337-45.
Konovalova A, Mitchell AM, Silhavy TJ. A lipoprotein/β-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane. Elife. 2016 ;5.
Konovalova A, Schwalm JA, Silhavy TJ. A Suppressor Mutation That Creates a Faster and More Robust σE Envelope Stress Response. J Bacteriol. 2016 ;198(17):2345-51.
2015
Konovalova A, Silhavy TJ. Outer membrane lipoprotein biogenesis: Lol is not the end. Philos Trans R Soc Lond B Biol Sci. 2015 ;370(1679).
2013
Grabowicz M, Yeh J, Silhavy TJ. Dominant negative lptE mutation that supports a role for LptE as a plug in the LptD barrel. J Bacteriol. 2013 ;195(6):1327-34.