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2021
Song H, Burton AJ, Shirran SL, Fahrig-Kamarauskaitė J, Kaspar H, Muir TW, et al.. Engineering of a Peptide α-N-Methyltransferase to Methylate Non-Proteinogenic Amino Acids. Angew Chem Int Ed Engl. 2021 ;60(26):14319-14323.
Zhao S, Chuh KN, Zhang B, Dul BE, Thompson RE, Farrelly LA, et al. Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout. Proc Natl Acad Sci U S A. 2021 ;118(6).
2020
Anlas AA, Nelson CM. Living under Strain: How Epithelia Protect Their Genomes from Repeated Stretching. Biochemistry. 2020 ;59(30):2761-2763.
Leicher R, Ge EJ, Lin X, Reynolds MJ, Xie W, Walz T, et al. Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin. Proc Natl Acad Sci U S A. 2020 ;117(48):30465-30475.
P Garcia D, Leach RW, Wadsworth GM, Choudhary K, Li H, Aviran S, et al. Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP. Nat Commun. 2020 ;11(1):2173.
Seo KW, Kleiner RE. YTHDF2 Recognition of N-Methyladenosine (mA)-Modified RNA Is Associated with Transcript Destabilization. ACS Chem Biol. 2020 ;15(1):132-139.
2019
Nacev BA, Feng L, Bagert JD, Lemiesz AE, Gao JJ, Soshnev AA, et al. The expanding landscape of 'oncohistone' mutations in human cancers. Nature. 2019 ;567(7749):473-478.
Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. 2019 ;567(7749):535-539.
Albig C, Wang C, Dann GP, Wojcik F, Schauer T, Krause S, et al. JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila. Nat Commun. 2019 ;10(1):5343.
2018
vonHoldt BM, Ji SS, Aardema ML, Stahler DR, Udell MAR, Sinsheimer JS. Activity of Genes with Functions in Human Williams-Beuren Syndrome Is Impacted by Mobile Element Insertions in the Gray Wolf Genome. Genome Biol Evol. 2018 ;10(6):1546-1553.
Jeon J, McGinty RK, Muir TW, Kim J-A, Kim J. Crosstalk among Set1 complex subunits involved in H2B ubiquitylation-dependent H3K4 methylation. Nucleic Acids Res. 2018 ;46(21):11129-11143.
Morscher RJ, Ducker GS, Li SHsin-Jung, Mayer JA, Gitai Z, Sperl W, et al. Mitochondrial translation requires folate-dependent tRNA methylation. Nature. 2018 ;554(7690):128-132.
Park H-J, Lee K-W, Oh S, Yan R, Zhang J, Beach TG, et al. Protein Phosphatase 2A and Its Methylation Modulating Enzymes LCMT-1 and PME-1 Are Dysregulated in Tauopathies of Progressive Supranuclear Palsy and Alzheimer Disease. J Neuropathol Exp Neurol. 2018 ;77(2):139-148.
2017
Asam K, Staniszewski A, Zhang H, Melideo SL, Mazzeo A, Voronkov M, et al. Eicosanoyl-5-hydroxytryptamide (EHT) prevents Alzheimer's disease-related cognitive and electrophysiological impairments in mice exposed to elevated concentrations of oligomeric beta-amyloid. PLoS One. 2017 ;12(12):e0189413.
2016
Zhou L, Holt MT, Ohashi N, Zhao A, Müller MM, Wang B, et al.. Evidence that ubiquitylated H2B corrals hDot1L on the nucleosomal surface to induce H3K79 methylation. Nat Commun. 2016 ;7:10589.
Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, et al. Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape. Science. 2016 ;352(6287):844-9.
Su X, Wellen KE, Rabinowitz JD. Metabolic control of methylation and acetylation. Curr Opin Chem Biol. 2016 ;30:52-60.
Müller MM, Fierz B, Bittova L, Liszczak G, Muir TW. A two-state activation mechanism controls the histone methyltransferase Suv39h1. Nat Chem Biol. 2016 ;12(3):188-93.
2015
Holt MT, David Y, Pollock S, Tang Z, Jeon J, Kim J, et al. Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin. Proc Natl Acad Sci U S A. 2015 ;112(33):10365-70.
2014
DeHart CJ, Chahal JS, Flint SJ, Perlman DH. Extensive post-translational modification of active and inactivated forms of endogenous p53. Mol Cell Proteomics. 2014 ;13(1):1-17.
Basurto-Islas G, Blanchard J, Tung YChyn, Fernández JR, Voronkov M, Stock M, et al.. Therapeutic benefits of a component of coffee in a rat model of Alzheimer's disease. Neurobiol Aging. 2014 ;35(12):2701-2712.
2008
Xing Y, Li Z, Chen Y, Stock JB, Jeffrey PD, Shi Y. Structural mechanism of demethylation and inactivation of protein phosphatase 2A. Cell. 2008 ;133(1):154-63.