Publications
Computational modeling offers new insight into Drosophila germ granule development. Biophys J. 2022 ;121(8):1465-1482.
. The 3'UTR of the Drosophila CPEB translation factor gene orb2 plays a crucial role in spermatogenesis. Development. 2021 ;148(17).
. LuxT controls specific quorum-sensing-regulated behaviors in Vibrionaceae spp. via repression of qrr1, encoding a small regulatory RNA. PLoS Genet. 2021 ;17(4):e1009336.
. Mapping parameter spaces of biological switches. PLoS Comput Biol. 2021 ;17(2):e1008711.
. Mechanisms of epitranscriptomic gene regulation. Biopolymers. 2021 ;112(1):e23403.
. mTORC1 promotes cell growth via mA-dependent mRNA degradation. Mol Cell. 2021 ;81(10):2064-2075.e8.
. A neural mA/Ythdf pathway is required for learning and memory in Drosophila. Nat Commun. 2021 ;12(1):1458.
. Steric interactions and out-of-equilibrium processes control the internal organization of bacteria. Proc Natl Acad Sci U S A. 2021 ;118(43).
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Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cell Rep. 2020 ;31(12):107783.
. Sequence-Independent Self-Assembly of Germ Granule mRNAs into Homotypic Clusters. Mol Cell. 2020 ;78(5):941-950.e12.
. YTHDF2 Recognition of N-Methyladenosine (mA)-Modified RNA Is Associated with Transcript Destabilization. ACS Chem Biol. 2020 ;15(1):132-139.
. Concerted 2-5A-Mediated mRNA Decay and Transcription Reprogram Protein Synthesis in the dsRNA Response. Mol Cell. 2019 ;75(6):1218-1228.e6.
. The CPEB Protein Orb Specifies Oocyte Fate by a 3'UTR-Dependent Autoregulatory Loop. Genetics. 2019 ;213(4):1431-1446.
. The CPEB translational regulator, Orb, functions together with Par proteins to polarize the Drosophila oocyte. PLoS Genet. 2019 ;15(3):e1008012.
. Long Noncoding RNA GMAN, Up-regulated in Gastric Cancer Tissues, Is Associated With Metastasis in Patients and Promotes Translation of Ephrin A1 by Competitively Binding GMAN-AS. Gastroenterology. 2019 ;156(3):676-691.e11.
. Nervous system-wide profiling of presynaptic mRNAs reveals regulators of associative memory. Sci Rep. 2019 ;9(1):20314.
. Serine Metabolism Supports Macrophage IL-1β Production. Cell Metab. 2019 ;29(4):1003-1011.e4.
. Changes in mRNA abundance drive shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription. Elife. 2018 ;7.
. Distinct -acting elements mediate targeting and clustering of polar granule mRNAs. Development. 2018 ;145(22).
. Genome-wide real-time in vivo transcriptional dynamics during Plasmodium falciparum blood-stage development. Nat Commun. 2018 ;9(1):2656.
. Live Imaging of mRNA Synthesis in Drosophila. Methods Mol Biol. 2018 ;1649:349-357.
. Paip2 is localized to active promoters and loaded onto nascent mRNA in Drosophila. Cell Cycle. 2018 ;17(14):1708-1720.
. Post-transcriptional gene regulation by an Hfq-independent small RNA in Caulobacter crescentus. Nucleic Acids Res. 2018 ;46(20):10969-10982.
. Single mRNA Molecule Detection in Drosophila. Methods Mol Biol. 2018 ;1649:127-142.
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