Publications
Phage Infection Restores PQS Signaling and Enhances Growth of a Pseudomonas aeruginosa Quorum-Sensing Mutant. J Bacteriol. 2022 ;204(5):e0055721.
. The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in . Microbiol Spectr. 2022 ;10(1):e0210821.
. A biophysical limit for quorum sensing in biofilms. Proc Natl Acad Sci U S A. 2021 ;118(21).
. bZIP11 Is a Susceptibility Factor During Infection. Mol Plant Microbe Interact. 2021 ;34(4):439-447.
. CrvA and CrvB form a curvature-inducing module sufficient to induce cell-shape complexity in Gram-negative bacteria. Nat Microbiol. 2021 ;6(7):910-920.
. FisB relies on homo-oligomerization and lipid binding to catalyze membrane fission in bacteria. PLoS Biol. 2021 ;19(6):e3001314.
. Inverse regulation of biofilm dispersal by polyamine signals. Elife. 2021 ;10.
. LuxT controls specific quorum-sensing-regulated behaviors in Vibrionaceae spp. via repression of qrr1, encoding a small regulatory RNA. PLoS Genet. 2021 ;17(4):e1009336.
. Saccharomyces cerevisiae Requires To Produce 4-Hydroxy-5-Methylfuran-3(2H)-One, a Mimic of the Bacterial Quorum-Sensing Autoinducer AI-2. mBio. 2021 ;12(2).
. Trapping a cross-linked lysine-tryptophan radical in the catalytic cycle of the radical SAM enzyme SuiB. Proc Natl Acad Sci U S A. 2021 ;118(21).
. AimB Is a Small Protein Regulator of Cell Size and MreB Assembly. Biophys J. 2020 ;119(3):593-604.
. CanE, an Iron/2-Oxoglutarate-Dependent Lasso Peptide Hydroxylase from . ACS Chem Biol. 2020 ;15(4):890-894.
. Cell position fates and collective fountain flow in bacterial biofilms revealed by light-sheet microscopy. Science. 2020 ;369(6499):71-77.
. Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa. PLoS Pathog. 2020 ;16(9):e1008867.
. Discovery of PqsE Thioesterase Inhibitors for Using DNA-Encoded Small Molecule Library Screening. ACS Chem Biol. 2020 ;15(2):446-456.
. Discovery of quorum quenchers targeting the membrane-embedded sensor domain of the receptor histidine kinase, AgrC. Chem Commun (Camb). 2020 ;56(76):11223-11226.
. . Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na channels in nanodisc. Proc Natl Acad Sci U S A. 2020 ;117(25):14187-14193.
. Identification of signaling pathways, matrix-digestion enzymes, and motility components controlling biofilm dispersal. Proc Natl Acad Sci U S A. 2020 ;117(51):32639-32647.
. Mechanism underlying autoinducer recognition in the DPO-VqmA quorum-sensing pathway. J Biol Chem. 2020 ;295(10):2916-2931.
. Multi-Omic Analyses Provide Links between Low-Dose Antibiotic Treatment and Induction of Secondary Metabolism in Burkholderia thailandensis. mBio. 2020 ;11(1).
. Reporter-Guided Transposon Mutant Selection for Activation of Silent Gene Clusters in Burkholderia thailandensis. Chembiochem. 2020 ;21(13):1826-1831.
. The Vibrio cholerae Quorum-Sensing Protein VqmA Integrates Cell Density, Environmental, and Host-Derived Cues into the Control of Virulence. mBio. 2020 ;11(4).
. Vibrio fischeri siderophore production drives competitive exclusion during dual-species growth. Mol Microbiol. 2020 ;114(2):244-261.
. Aliphatic Ether Bond Formation Expands the Scope of Radical SAM Enzymes in Natural Product Biosynthesis. J Am Chem Soc. 2019 ;141(27):10610-10615.
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