Publications
Globularity and protein function. J Biomol Struct Dyn. 2000 ;17 Suppl 1:87-8.
. An intein-based genetic selection allows the construction of a high-quality library of binary patterned de novo protein sequences. Protein Eng Des Sel. 2005 ;18(4):201-7.
. Protein reconstitution and three-dimensional domain swapping: benefits and constraints of covalency. Protein Sci. 2007 ;16(11):2317-33.
. Deep proteomics of the Xenopus laevis egg using an mRNA-derived reference database. Curr Biol. 2014 ;24(13):1467-1475.
. molBLOCKS: decomposing small molecule sets and uncovering enriched fragments. Bioinformatics. 2014 ;30(14):2081-3.
. Beyond the E-Value: Stratified Statistics for Protein Domain Prediction. PLoS Comput Biol. 2015 ;11(11):e1004509.
. Divergent evolution of a bifunctional de novo protein. Protein Sci. 2015 ;24(2):246-52.
. RAI2: Linking Retinoic Acid Signaling with Metastasis Suppression. Cancer Discov. 2015 ;5(5):466-8.
. Biophysical characterization of organelle-based RNA/protein liquid phases using microfluidics. Soft Matter. 2016 ;12(45):9142-9150.
. A de novo protein confers copper resistance in Escherichia coli. Protein Sci. 2016 ;25(7):1249-59.
. De Novo Proteins with Life-Sustaining Functions Are Structurally Dynamic. J Mol Biol. 2016 ;428(2 Pt A):399-411.
. Determining the Composition and Stability of Protein Complexes Using an Integrated Label-Free and Stable Isotope Labeling Strategy. Methods Mol Biol. 2016 ;1410:39-63.
. Long-term dynamics of multisite phosphorylation. Mol Biol Cell. 2016 ;27(14):2331-40.
. Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors. Nat Med. 2017 ;23(2):235-241.
. mTOR Inhibition Restores Amino Acid Balance in Cells Dependent on Catabolism of Extracellular Protein. Mol Cell. 2017 ;67(6):936-946.e5.
. Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets. Cell. 2017 ;168(1-2):159-171.e14.
. An Atypical Mechanism of Split Intein Molecular Recognition and Folding. J Am Chem Soc. 2018 ;140(37):11791-11799.
. How many human proteoforms are there?. Nat Chem Biol. 2018 ;14(3):206-214.
. Improved protein splicing using embedded split inteins. Protein Sci. 2018 ;27(3):614-619.
. Optogenetic Reconstitution for Determining the Form and Function of Membraneless Organelles. Biochemistry. 2018 ;57(17):2432-2436.
. Orchestration of protein acetylation as a toggle for cellular defense and virus replication. Nat Commun. 2018 ;9(1):4967.
. Protein lipoylation: an evolutionarily conserved metabolic regulator of health and disease. Curr Opin Chem Biol. 2018 ;42:76-85.
. Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli. Cell Syst. 2018 ;6(6):655-663.e5.
. A bright future: optogenetics to dissect the spatiotemporal control of cell behavior. Curr Opin Chem Biol. 2019 ;48:106-113.
. Considerations for Identifying Endogenous Protein Complexes from Tissue via Immunoaffinity Purification and Quantitative Mass Spectrometry. Methods Mol Biol. 2019 ;1977:115-143.
.