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2021
Lafontaine DLJ, Riback JA, Bascetin R, Brangwynne CP. The nucleolus as a multiphase liquid condensate. Nat Rev Mol Cell Biol. 2021 ;22(3):165-182.
Minhas PS, Latif-Hernandez A, McReynolds MR, Durairaj AS, Wang Q, Rubin A, et al. Restoring metabolism of myeloid cells reverses cognitive decline in ageing. Nature. 2021 ;590(7844):122-128.
2020
Chini CCS, Peclat TR, Warner GM, Kashyap S, Espindola-Netto JMachado, de Oliveira GC, et al. CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD and NMN levels. Nat Metab. 2020 ;2(11):1284-1304.
Templeman NM, Cota V, Keyes W, Kaletsky R, Murphy CT. CREB Non-autonomously Controls Reproductive Aging through Hedgehog/Patched Signaling. Dev Cell. 2020 ;54(1):92-105.e5.
Parkhitko AA, Ramesh D, Wang L, Leshchiner D, Filine E, Binari R, et al. Downregulation of the tyrosine degradation pathway extends lifespan. Elife. 2020 ;9.
Roussarie J-P, Yao V, Rodriguez-Rodriguez P, Oughtred R, Rust J, Plautz Z, et al. Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis. Neuron. 2020 ;107(5):821-835.e12.
Notterman DA, Schneper L. Telomere Time-Why We Should Treat Biological Age Cautiously. JAMA Netw Open. 2020 ;3(5):e204352.
Kaletsky R, Murphy CT. Transcriptional Profiling of C. elegans Adult Cells and Tissues with Age. Methods Mol Biol. 2020 ;2144:177-186.
2019
Minhas PS, Liu L, Moon PK, Joshi AU, Dove C, Mhatre S, et al. Macrophage de novo NAD synthesis specifies immune function in aging and inflammation. Nat Immunol. 2019 ;20(1):50-63.
Betsinger CN, Cristea IM. Mitochondrial Function, Metabolic Regulation, and Human Disease Viewed through the Prism of Sirtuin 4 (SIRT4) Functions. J Proteome Res. 2019 ;18(5):1929-1938.
2018
Templeman NM, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, et al. Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity. Curr Biol. 2018 ;28(5):753-760.e4.
Templeman NM, Murphy CT. Regulation of reproduction and longevity by nutrient-sensing pathways. J Cell Biol. 2018 ;217(1):93-106.
2017
Mirzaei M, Gupta VB, Chick JM, Greco TM, Wu Y, Chitranshi N, et al. Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes. Sci Rep. 2017 ;7(1):12685.
2016
Kaletsky R, Lakhina V, Arey R, Williams A, Landis J, Ashraf J, et al. The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators. Nature. 2016 ;529(7584):92-6.
Frederick DW, Loro E, Liu L, Davila A, Chellappa K, Silverman IM, et al. Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle. Cell Metab. 2016 ;24(2):269-82.
Tetruashvily MM, McDonald MA, Frietze KK, Boulanger LM. MHCI promotes developmental synapse elimination and aging-related synapse loss at the vertebrate neuromuscular junction. Brain Behav Immun. 2016 ;56:197-208.
Li L-B, Lei H, Arey RN, Li P, Liu J, Murphy CT, et al. The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory. Curr Biol. 2016 ;26(5):605-15.
Charruau P, Johnston RA, Stahler DR, Lea A, Snyder-Mackler N, Smith DW, et al. Pervasive Effects of Aging on Gene Expression in Wild Wolves. Mol Biol Evol. 2016 ;33(8):1967-78.
Snir S, vonHoldt BM, Pellegrini M. A Statistical Framework to Identify Deviation from Time Linearity in Epigenetic Aging. PLoS Comput Biol. 2016 ;12(11):e1005183.
2015
DiLoreto R, Murphy CT. The cell biology of aging. Mol Biol Cell. 2015 ;26(25):4524-31.
Fernández-Capetillo Ó, Yan N, Dionne J, Bassett D, Sebastian S, Hendon C, et al.. Hopes for the year ahead. Nature. 2015 ;517(7532):111-3.
Peshkin L, Wühr M, Pearl E, Haas W, Freeman RM, Gerhart JC, et al.. On the Relationship of Protein and mRNA Dynamics in Vertebrate Embryonic Development. Dev Cell. 2015 ;35(3):383-94.
2014
McKoy AF, Chen J, Schüpbach T, Hecht MH. Structure-activity relationships for a series of compounds that inhibit aggregation of the Alzheimer's peptide, Aβ42. Chem Biol Drug Des. 2014 ;84(5):505-12.