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2020
Zhang C, Seyedsayamdost MR. Discovery of a Cryptic Depsipeptide from Streptomyces ghanaensis via MALDI-MS-Guided High-Throughput Elicitor Screening. Angew Chem Int Ed Engl. 2020 ;59(51):23005-23009.
Valastyan JS, Tota MR, Taylor IR, Stergioula V, Hone GAB, Smith CD, et al. Discovery of PqsE Thioesterase Inhibitors for Using DNA-Encoded Small Molecule Library Screening. ACS Chem Biol. 2020 ;15(2):446-456.
Xie Q, Wiedmann MM, Zhao A, Pagan IR, Novick RP, Suga H, et al. Discovery of quorum quenchers targeting the membrane-embedded sensor domain of the receptor histidine kinase, AgrC. Chem Commun (Camb). 2020 ;56(76):11223-11226.
Martin JK, Sheehan JP, Bratton BP, Moore GM, Mateus A, Li SHsin-Jung, et al. A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance. Cell. 2020 ;181(7):1518-1532.e14.
2019
Cheung-Lee WLing, Parry ME, Cartagena AJaramillo, Darst SA, A Link J. Discovery and structure of the antimicrobial lasso peptide citrocin. J Biol Chem. 2019 ;294(17):6822-6830.
Okada BK, Li A, Seyedsayamdost MR. Identification of the Hypertension Drug Guanfacine as an Antivirulence Agent in Pseudomonas aeruginosa. Chembiochem. 2019 ;20(15):2005-2011.
Hart EM, Mitchell AM, Konovalova A, Grabowicz M, Sheng J, Han X, et al. A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier. Proc Natl Acad Sci U S A. 2019 ;116(43):21748-21757.
2016
Orman MA, Henry TC, DeCoste CJ, Brynildsen MP. Analyzing Persister Physiology with Fluorescence-Activated Cell Sorting. Methods Mol Biol. 2016 ;1333:83-100.
Orman MA, Brynildsen MP. Persister formation in Escherichia coli can be inhibited by treatment with nitric oxide. Free Radic Biol Med. 2016 ;93:145-54.
2015
Miller LC, O'Loughlin CT, Zhang Z, Siryaporn A, Silpe JE, Bassler BL, et al. Development of potent inhibitors of pyocyanin production in Pseudomonas aeruginosa. J Med Chem. 2015 ;58(3):1298-306.
2009
Swem LR, Swem DL, O'Loughlin CT, Gatmaitan R, Zhao B, Ulrich SM, et al. A quorum-sensing antagonist targets both membrane-bound and cytoplasmic receptors and controls bacterial pathogenicity. Mol Cell. 2009 ;35(2):143-53.