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Lee SRak, Seyedsayamdost MR. Induction of Diverse Cryptic Fungal Metabolites by Steroids and Channel Blockers. Angew Chem Int Ed Engl. 2022 ;61(29):e202204519.
Do T, Thokkadam A, Leach R, A Link J. Phenotype-Guided Comparative Genomics Identifies the Complete Transport Pathway of the Antimicrobial Lasso Peptide Ubonodin in . ACS Chem Biol. 2022 ;17(8):2332-2343.
Taylor IR, Jeffrey PD, Moustafa DA, Goldberg JB, Bassler BL. The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against . Biochemistry. 2022 ;61(17):1894-1903.
Simanek KA, Taylor IR, Richael EK, Lasek-Nesselquist E, Bassler BL, Paczkowski JE. The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in . Microbiol Spectr. 2022 ;10(1):e0210821.
Murawski AM, Rittenbach K, DeCoste CJ, Laevsky G, Brynildsen MP. Counting Chromosomes in Individual Bacteria to Quantify Their Impacts on Persistence. Methods Mol Biol. 2021 ;2357:125-146.
Murawski AM, Brynildsen MP. Ploidy is an important determinant of fluoroquinolone persister survival. Curr Biol. 2021 ;31(10):2039-2050.e7.
Rued BE, Covington BC, Bushin LB, Szewczyk G, Laczkovich I, Seyedsayamdost MR, et al. Quorum Sensing in Streptococcus mutans Regulates Production of Tryglysin, a Novel RaS-RiPP Antimicrobial Compound. mBio. 2021 ;12(2).
Lemma AS, Brynildsen MP. Toxin Induction or Inhibition of Transcription or Translation Posttreatment Increases Persistence to Fluoroquinolones. mBio. 2021 ;12(4):e0198321.
Claesen J, Spagnolo JB, Ramos SFlores, Kurita KL, Byrd AL, Aksenov AA, et al. A antibiotic modulates human skin microbiota composition in hair follicles. Sci Transl Med. 2020 ;12(570).
Zhang C, Seyedsayamdost MR. Discovery of a Cryptic Depsipeptide from Streptomyces ghanaensis via MALDI-MS-Guided High-Throughput Elicitor Screening. Angew Chem Int Ed Engl. 2020 ;59(51):23005-23009.
Cheung-Lee WLing, Parry ME, Zong C, Cartagena AJaramillo, Darst SA, Connell ND, et al. Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex. Chembiochem. 2020 ;21(9):1335-1340.
Martin JK, Sheehan JP, Bratton BP, Moore GM, Mateus A, Li SHsin-Jung, et al. A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance. Cell. 2020 ;181(7):1518-1532.e14.
Bridges AA, Fei C, Bassler BL. Identification of signaling pathways, matrix-digestion enzymes, and motility components controlling biofilm dispersal. Proc Natl Acad Sci U S A. 2020 ;117(51):32639-32647.
Li A, Mao D, Yoshimura A, Rosen PC, W Martin L, Gallant É, et al.. Multi-Omic Analyses Provide Links between Low-Dose Antibiotic Treatment and Induction of Secondary Metabolism in Burkholderia thailandensis. mBio. 2020 ;11(1).
Park J-D, Moon K, Miller C, Rose J, Xu F, Ebmeier CC, et al. Thailandenes, Cryptic Polyene Natural Products Isolated from Using Phenotype-Guided Transposon Mutagenesis. ACS Chem Biol. 2020 ;15(5):1195-1203.
Moon K, Xu F, Zhang C, Seyedsayamdost MR. Bioactivity-HiTES Unveils Cryptic Antibiotics Encoded in Actinomycete Bacteria. ACS Chem Biol. 2019 ;14(4):767-774.
Moon K, Xu F, Seyedsayamdost MR. Cebulantin, a Cryptic Lanthipeptide Antibiotic Uncovered Using Bioactivity-Coupled HiTES. Angew Chem Int Ed Engl. 2019 ;58(18):5973-5977.
Aedo SJ, Ma HR, Brynildsen MP. Checks and Balances with Use of the Keio Collection for Phenotype Testing. Methods Mol Biol. 2019 ;1927:125-138.
Balaban NQ, Helaine S, Lewis K, Ackermann M, Aldridge B, Andersson DI, et al. Definitions and guidelines for research on antibiotic persistence. Nat Rev Microbiol. 2019 ;17(7):441-448.
Cheung-Lee WLing, Parry ME, Cartagena AJaramillo, Darst SA, A Link J. Discovery and structure of the antimicrobial lasso peptide citrocin. J Biol Chem. 2019 ;294(17):6822-6830.
Barrett TC, Mok WWK, Murawski AM, Brynildsen MP. Enhanced antibiotic resistance development from fluoroquinolone persisters after a single exposure to antibiotic. Nat Commun. 2019 ;10(1):1177.
Okada BK, Li A, Seyedsayamdost MR. Identification of the Hypertension Drug Guanfacine as an Antivirulence Agent in Pseudomonas aeruginosa. Chembiochem. 2019 ;20(15):2005-2011.
Liu M, El-Hossary EM, Oelschlaeger TA, Donia MS, Quinn RJ, Abdelmohsen URamadan. Potential of marine natural products against drug-resistant bacterial infections. Lancet Infect Dis. 2019 ;19(7):e237-e245.
Hart EM, Mitchell AM, Konovalova A, Grabowicz M, Sheng J, Han X, et al. A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier. Proc Natl Acad Sci U S A. 2019 ;116(43):21748-21757.
Braffman NR, Piscotta FJ, Hauver J, Campbell EA, A Link J, Darst SA. Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc Natl Acad Sci U S A. 2019 ;116(4):1273-1278.