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2019
Paczkowski JE, McCready AR, Cong J-P, Li Z, Jeffrey PD, Smith CD, et al. An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. ACS Chem Biol. 2019 ;14(3):378-389.
McCready AR, Paczkowski JE, Cong J-P, Bassler BL. An autoinducer-independent RhlR quorum-sensing receptor enables analysis of RhlR regulation. PLoS Pathog. 2019 ;15(6):e1007820.
Sanfilippo JE, Lorestani A, Koch MD, Bratton BP, Siryaporn A, Stone HA, et al. Microfluidic-based transcriptomics reveal force-independent bacterial rheosensing. Nat Microbiol. 2019 ;4(8):1274-1281.
Mukherjee S, Jemielita M, Stergioula V, Tikhonov M, Bassler BL. Photosensing and quorum sensing are integrated to control Pseudomonas aeruginosa collective behaviors. PLoS Biol. 2019 ;17(12):e3000579.
Moore RS, Kaletsky R, Murphy CT. Piwi/PRG-1 Argonaute and TGF-β Mediate Transgenerational Learned Pathogenic Avoidance. Cell. 2019 ;177(7):1827-1841.e12.
McCready AR, Paczkowski JE, Henke BR, Bassler BL. Structural determinants driving homoserine lactone ligand selection in the LasR quorum-sensing receptor. Proc Natl Acad Sci U S A. 2019 ;116(1):245-254.
Chuang SK, Vrla GD, Fröhlich KS, Gitai Z. Surface association sensitizes Pseudomonas aeruginosa to quorum sensing. Nat Commun. 2019 ;10(1):4118.
2018
Kannan A, Yang Z, Kim MKevin, Stone HA, Siryaporn A. Dynamic switching enables efficient bacterial colonization in flow. Proc Natl Acad Sci U S A. 2018 ;115(21):5438-5443.
Trivedi RR, Crooks JA, Auer GK, Pendry J, Foik IP, Siryaporn A, et al. Mechanical Genomic Studies Reveal the Role of d-Alanine Metabolism in Pseudomonas aeruginosa Cell Stiffness. mBio. 2018 ;9(5).
Mukherjee S, Moustafa DA, Stergioula V, Smith CD, Goldberg JB, Bassler BL. The PqsE and RhlR proteins are an autoinducer synthase-receptor pair that control virulence and biofilm development in . Proc Natl Acad Sci U S A. 2018 ;115(40):E9411-E9418.
2017
Paczkowski JE, Mukherjee S, McCready AR, Cong J-P, Aquino CJ, Kim H, et al. Flavonoids Suppress Virulence through Allosteric Inhibition of Quorum-sensing Receptors. J Biol Chem. 2017 ;292(10):4064-4076.
Nadell CD, Ricaurte D, Yan J, Drescher K, Bassler BL. Flow environment and matrix structure interact to determine spatial competition in biofilms. Elife. 2017 ;6.
Robinson JL, Jaslove JM, Murawski AM, Fazen CH, Brynildsen MP. An integrated network analysis reveals that nitric oxide reductase prevents metabolic cycling of nitric oxide by Pseudomonas aeruginosa. Metab Eng. 2017 ;41:67-81.
Høyland-Kroghsbo NM, Paczkowski J, Mukherjee S, Broniewski J, Westra E, Bondy-Denomy J, et al.. Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system. Proc Natl Acad Sci U S A. 2017 ;114(1):131-135.
Mukherjee S, Moustafa D, Smith CD, Goldberg JB, Bassler BL. The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer. PLoS Pathog. 2017 ;13(7):e1006504.
2016
Robinson JL, Brynildsen MP. Discovery and dissection of metabolic oscillations in the microaerobic nitric oxide response network of Escherichia coli. Proc Natl Acad Sci U S A. 2016 ;113(12):E1757-66.
Henry TC, Brynildsen MP. Quantifying Current Events Identifies a Novel Endurance Regulator. Trends Microbiol. 2016 ;24(5):324-326.
Inclan YF, Persat A, Greninger A, Von Dollen J, Johnson J, Krogan N, et al. A scaffold protein connects type IV pili with the Chp chemosensory system to mediate activation of virulence signaling in Pseudomonas aeruginosa. Mol Microbiol. 2016 ;101(4):590-605.
2015
Siryaporn A, Kim MKevin, Shen Y, Stone HA, Gitai Z. Colonization, competition, and dispersal of pathogens in fluid flow networks. Curr Biol. 2015 ;25(9):1201-7.
Miller LC, O'Loughlin CT, Zhang Z, Siryaporn A, Silpe JE, Bassler BL, et al. Development of potent inhibitors of pyocyanin production in Pseudomonas aeruginosa. J Med Chem. 2015 ;58(3):1298-306.
Persat A, Nadell CD, Kim MKevin, Ingremeau F, Siryaporn A, Drescher K, et al. The mechanical world of bacteria. Cell. 2015 ;161(5):988-997.
Persat A, Inclan YF, Engel JN, Stone HA, Gitai Z. Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2015 ;112(24):7563-8.
2013
Drescher K, Shen Y, Bassler BL, Stone HA. Biofilm streamers cause catastrophic disruption of flow with consequences for environmental and medical systems. Proc Natl Acad Sci U S A. 2013 ;110(11):4345-50.
O'Loughlin CT, Miller LC, Siryaporn A, Drescher K, Semmelhack MF, Bassler BL. A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proc Natl Acad Sci U S A. 2013 ;110(44):17981-6.
2012
Rutherford ST, Bassler BL. Bacterial quorum sensing: its role in virulence and possibilities for its control. Cold Spring Harb Perspect Med. 2012 ;2(11).