Publications
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Filters: Keyword is Pseudomonas aeruginosa [Clear All Filters]
distinguishes surfaces by stiffness using retraction of type IV pili. Proc Natl Acad Sci U S A. 2022 ;119(20):e2119434119.
. Phage Infection Restores PQS Signaling and Enhances Growth of a Pseudomonas aeruginosa Quorum-Sensing Mutant. J Bacteriol. 2022 ;204(5):e0055721.
. The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in . Microbiol Spectr. 2022 ;10(1):e0210821.
. Competitive binding of independent extension and retraction motors explains the quantitative dynamics of type IV pili. Proc Natl Acad Sci U S A. 2021 ;118(8).
. Inhibitor Mimetic Mutations in the PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production. ACS Chem Biol. 2021 ;16(4):740-752.
. Protocol for transgenerational learned pathogen avoidance behavior assays in . STAR Protoc. 2021 ;2(1):100384.
. Pseudomonas aeruginosa detachment from surfaces via a self-made small molecule. J Biol Chem. 2021 ;296:100279.
. Pseudomonas aeruginosa prioritizes detoxification of hydrogen peroxide over nitric oxide. BMC Res Notes. 2021 ;14(1):120.
. C. elegans interprets bacterial non-coding RNAs to learn pathogenic avoidance. Nature. 2020 ;586(7829):445-451.
. Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa. PLoS Pathog. 2020 ;16(9):e1008867.
. Discovery of PqsE Thioesterase Inhibitors for Using DNA-Encoded Small Molecule Library Screening. ACS Chem Biol. 2020 ;15(2):446-456.
. A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance. Cell. 2020 ;181(7):1518-1532.e14.
. An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. ACS Chem Biol. 2019 ;14(3):378-389.
. An autoinducer-independent RhlR quorum-sensing receptor enables analysis of RhlR regulation. PLoS Pathog. 2019 ;15(6):e1007820.
. Identification of the Hypertension Drug Guanfacine as an Antivirulence Agent in Pseudomonas aeruginosa. Chembiochem. 2019 ;20(15):2005-2011.
. Microfluidic-based transcriptomics reveal force-independent bacterial rheosensing. Nat Microbiol. 2019 ;4(8):1274-1281.
. Photosensing and quorum sensing are integrated to control Pseudomonas aeruginosa collective behaviors. PLoS Biol. 2019 ;17(12):e3000579.
. Piwi/PRG-1 Argonaute and TGF-β Mediate Transgenerational Learned Pathogenic Avoidance. Cell. 2019 ;177(7):1827-1841.e12.
. Structural determinants driving homoserine lactone ligand selection in the LasR quorum-sensing receptor. Proc Natl Acad Sci U S A. 2019 ;116(1):245-254.
. Surface association sensitizes Pseudomonas aeruginosa to quorum sensing. Nat Commun. 2019 ;10(1):4118.
. Dynamic switching enables efficient bacterial colonization in flow. Proc Natl Acad Sci U S A. 2018 ;115(21):5438-5443.
. Mechanical Genomic Studies Reveal the Role of d-Alanine Metabolism in Pseudomonas aeruginosa Cell Stiffness. mBio. 2018 ;9(5).
. The PqsE and RhlR proteins are an autoinducer synthase-receptor pair that control virulence and biofilm development in . Proc Natl Acad Sci U S A. 2018 ;115(40):E9411-E9418.
. Flavonoids Suppress Virulence through Allosteric Inhibition of Quorum-sensing Receptors. J Biol Chem. 2017 ;292(10):4064-4076.
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