Publications
The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule. Mol Microbiol. 2001 ;41(2):463-76.
. Statistical significance of variables driving systematic variation in high-dimensional data. Bioinformatics. 2015 ;31(4):545-54.
. Admixture mapping identifies introgressed genomic regions in North American canids. Mol Ecol. 2016 ;25(11):2443-53.
. Ancient hybridization and genomic stabilization in a swordtail fish. Mol Ecol. 2016 ;25(11):2661-79.
. Developmental genetics in emerging rodent models: case studies and perspectives. Curr Opin Genet Dev. 2016 ;39:182-186.
. Genomic Flatlining in the Endangered Island Fox. Curr Biol. 2016 ;26(9):1183-9.
. GIANT API: an application programming interface for functional genomics. Nucleic Acids Res. 2016 ;44(W1):W587-92.
. Differential analysis between somatic mutation and germline variation profiles reveals cancer-related genes. Genome Med. 2017 ;9(1):79.
. Genomic targeting of epigenetic probes using a chemically tailored Cas9 system. Proc Natl Acad Sci U S A. 2017 ;114(4):681-686.
. Mouse genomic screen reveals novel host regulator of metastasis. Genome Biol. 2017 ;18(1):31.
. Network-Based Coverage of Mutational Profiles Reveals Cancer Genes. Cell Syst. 2017 ;5(3):221-229.e4.
. GIANT 2.0: genome-scale integrated analysis of gene networks in tissues. Nucleic Acids Res. 2018 ;46(W1):W65-W70.
. Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle. Mol Cell Endocrinol. 2018 ;471:22-32.
. Interpretation of an individual functional genomics experiment guided by massive public data. Nat Methods. 2018 ;15(12):1049-1052.
. A Computational Framework for Genome-wide Characterization of the Human Disease Landscape. Cell Syst. 2019 ;8(2):152-162.e6.
. A genome-wide algal mutant library and functional screen identifies genes required for eukaryotic photosynthesis. Nat Genet. 2019 ;51(4):627-635.
. Nervous system-wide profiling of presynaptic mRNAs reveals regulators of associative memory. Sci Rep. 2019 ;9(1):20314.
. Selene: a PyTorch-based deep learning library for sequence data. Nat Methods. 2019 ;16(4):315-318.
. Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk. Nat Genet. 2019 ;51(6):973-980.
. Genomic analyses implicate noncoding de novo variants in congenital heart disease. Nat Genet. 2020 ;52(8):769-777.
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