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2020
Carrasco-López C, Zhao EM, Gil AA, Alam N, Toettcher JE, Avalos JL. Development of light-responsive protein binding in the monobody non-immunoglobulin scaffold. Nat Commun. 2020 ;11(1):4045.
Hart EM, Gupta M, Wühr M, Silhavy TJ. The gain-of-function allele bypasses the essential requirement for BamD in β-barrel outer membrane protein assembly. Proc Natl Acad Sci U S A. 2020 ;117(31):18737-18743.
2019
Paczkowski JE, McCready AR, Cong J-P, Li Z, Jeffrey PD, Smith CD, et al. An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. ACS Chem Biol. 2019 ;14(3):378-389.
Cheung-Lee WLing, Parry ME, Cartagena AJaramillo, Darst SA, A Link J. Discovery and structure of the antimicrobial lasso peptide citrocin. J Biol Chem. 2019 ;294(17):6822-6830.
Stubbe JA, Seyedsayamdost MR. Discovery of a New Class I Ribonucleotide Reductase with an Essential DOPA Radical and NO Metal as an Initiator of Long-Range Radical Transfer. Biochemistry. 2019 ;58(6):435-437.
Barrett TC, Mok WWK, Murawski AM, Brynildsen MP. Enhanced antibiotic resistance development from fluoroquinolone persisters after a single exposure to antibiotic. Nat Commun. 2019 ;10(1):1177.
Hart EM, O'Connell A, Tang K, Wzorek JS, Grabowicz M, Kahne D, et al. Fine-Tuning of σ Activation Suppresses Multiple Assembly-Defective Mutations in Escherichia coli. J Bacteriol. 2019 ;201(11).
Silhavy TJ, Mitchell AM. Genetic Analysis of Protein Translocation. Protein J. 2019 ;38(3):217-228.
Chou WKang, Brynildsen MP. Loss of DksA leads to multi-faceted impairment of nitric oxide detoxification by Escherichia coli. Free Radic Biol Med. 2019 ;130:288-296.
Park JO, Tanner LB, Wei MH, Khana DB, Jacobson TB, Zhang Z, et al. Near-equilibrium glycolysis supports metabolic homeostasis and energy yield. Nat Chem Biol. 2019 ;15(10):1001-1008.
Ricci DP, Silhavy TJ. Outer Membrane Protein Insertion by the β-barrel Assembly Machine. EcoSal Plus. 2019 ;8(2).
Piscotta FJ, Jeffrey PD, A Link J. ParST is a widespread toxin-antitoxin module that targets nucleotide metabolism. Proc Natl Acad Sci U S A. 2019 ;116(3):826-834.
Freije CA, Myhrvold C, Boehm CK, Lin AE, Welch NL, Carter A, et al. Programmable Inhibition and Detection of RNA Viruses Using Cas13. Mol Cell. 2019 ;76(5):826-837.e11.
Hart EM, Mitchell AM, Konovalova A, Grabowicz M, Sheng J, Han X, et al. A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier. Proc Natl Acad Sci U S A. 2019 ;116(43):21748-21757.
Aedo SJ, Orman MA, Brynildsen MP. Stationary phase persister formation in Escherichia coli can be suppressed by piperacillin and PBP3 inhibition. BMC Microbiol. 2019 ;19(1):140.
Hart EM, Gupta M, Wühr M, Silhavy TJ. The Synthetic Phenotype of Δ Δ Double Mutants Results from a Lethal Jamming of the Bam Complex by the Lipoprotein RcsF. mBio. 2019 ;10(3).
Adolfsen KJ, Chou WKang, Brynildsen MP. Transcriptional Regulation Contributes to Prioritized Detoxification of Hydrogen Peroxide over Nitric Oxide. J Bacteriol. 2019 ;201(14).
Schober AF, Mathis AD, Ingle C, Park JO, Chen L, Rabinowitz JD, et al. A Two-Enzyme Adaptive Unit within Bacterial Folate Metabolism. Cell Rep. 2019 ;27(11):3359-3370.e7.
2018
Hecht MH, Zarzhitsky S, Karas C, Chari S. Are natural proteins special? Can we do that?. Curr Opin Struct Biol. 2018 ;48:124-132.
Hoegler KJ, Hecht MH. Artificial Gene Amplification in Escherichia coli Reveals Numerous Determinants for Resistance to Metal Toxicity. J Mol Evol. 2018 ;86(2):103-110.
Bushin LB, Clark KA, Pelczer I, Seyedsayamdost MR. Charting an Unexplored Streptococcal Biosynthetic Landscape Reveals a Unique Peptide Cyclization Motif. J Am Chem Soc. 2018 ;140(50):17674-17684.
Lalwani MA, Zhao EM, Avalos JL. Current and future modalities of dynamic control in metabolic engineering. Curr Opin Biotechnol. 2018 ;52:56-65.
Mitchell AM, Srikumar T, Silhavy TJ. Cyclic Enterobacterial Common Antigen Maintains the Outer Membrane Permeability Barrier of Escherichia coli in a Manner Controlled by YhdP. mBio. 2018 ;9(4).
Donnelly AE, Murphy GS, Digianantonio KM, Hecht MH. A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli. Nat Chem Biol. 2018 ;14(3):253-255.
Li SHsin-Jung, Li Z, Park JO, King CG, Rabinowitz JD, Wingreen NS, et al. Escherichia coli translation strategies differ across carbon, nitrogen and phosphorus limitation conditions. Nat Microbiol. 2018 ;3(8):939-947.