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2020
Xu Y, Zhang Y, García-Cañaveras JC, Guo L, Kan M, Yu S, et al.. Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells. Science. 2020 ;369(6502):397-403.
Vrla GD, Esposito M, Zhang C, Kang Y, Seyedsayamdost MR, Gitai Z. Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa. PLoS Pathog. 2020 ;16(9):e1008867.
Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, et al. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 2020 ;579(7800):586-591.
Gu B, Posfai E, Gertsenstein M, Rossant J. Efficient Generation of Large-Fragment Knock-In Mouse Models Using 2-Cell (2C)-Homologous Recombination (HR)-CRISPR. Curr Protoc Mouse Biol. 2020 ;10(1):e67.
Winer B, Edgel KA, Zou X, Sellau J, Hadiwidjojo S, Garver LS, et al. Identification of Plasmodium falciparum proteoforms from liver stage models. Malar J. 2020 ;19(1):10.
Wan L, Chong S, Xuan F, Liang A, Cui X, Gates L, et al. Impaired cell fate through gain-of-function mutations in a chromatin reader. Nature. 2020 ;577(7788):121-126.
Hermans D, Gautam S, García-Cañaveras JC, Gromer D, Mitra S, Spolski R, et al.. Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8 T cell stemness and antitumor immunity. Proc Natl Acad Sci U S A. 2020 ;117(11):6047-6055.
Liou CS, Sirk SJ, Diaz CAC, Klein AP, Fischer CR, Higginbottom SK, et al. A Metabolic Pathway for Activation of Dietary Glucosinolates by a Human Gut Symbiont. Cell. 2020 ;180(4):717-728.e19.
Gil AA, Carrasco-López C, Zhu L, Zhao EM, Ravindran PT, Wilson MZ, et al.. Optogenetic control of protein binding using light-switchable nanobodies. Nat Commun. 2020 ;11(1):4044.
Hartenian E, Gilbertson S, Federspiel JD, Cristea IM, Glaunsinger BA. RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters. PLoS Pathog. 2020 ;16(2):e1008269.
2019
Monsivais D, Peng J, Kang Y, Matzuk MM. Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma. Proc Natl Acad Sci U S A. 2019 ;116(9):3883-3892.
Laval K, Van Cleemput J, Vernejoul JB, Enquist LW. Alphaherpesvirus infection of mice primes PNS neurons to an inflammatory state regulated by TLR2 and type I IFN signaling. PLoS Pathog. 2019 ;15(11):e1008087.
Esposito M, Mondal N, Greco TM, Wei Y, Spadazzi C, Lin S-C, et al. Bone vascular niche E-selectin induces mesenchymal-epithelial transition and Wnt activation in cancer cells to promote bone metastasis. Nat Cell Biol. 2019 ;21(5):627-639.
Giovannucci A, Friedrich J, Gunn P, Kalfon J, Brown BL, Koay SAnn, et al. CaImAn an open source tool for scalable calcium imaging data analysis. Elife. 2019 ;8.
Zhang H, Brown RL, Wei Y, Zhao P, Liu S, Liu X, et al. CD44 splice isoform switching determines breast cancer stem cell state. Genes Dev. 2019 ;33(3-4):166-179.
Deverett B, Kislin M, Tank DW, Wang SS-H. Cerebellar disruption impairs working memory during evidence accumulation. Nat Commun. 2019 ;10(1):3128.
Federspiel JD, Tandon P, Wilczewski CM, Wasson L, Herring LE, Venkatesh SS, et al. Conservation and divergence of protein pathways in the vertebrate heart. PLoS Biol. 2019 ;17(9):e3000437.
Gaska JM, Parsons L, Balev M, Cirincione A, Wang W, Schwartz RE, et al. Conservation of cell-intrinsic immune responses in diverse nonhuman primate species. Life Sci Alliance. 2019 ;2(5).
Aiello NM, Kang Y. Context-dependent EMT programs in cancer metastasis. J Exp Med. 2019 ;216(5):1016-1026.
Zhu L, Richardson TM, Wacheul L, Wei M-T, Feric M, Whitney G, et al. Controlling the material properties and rRNA processing function of the nucleolus using light. Proc Natl Acad Sci U S A. 2019 ;116(35):17330-17335.
Gaska JM, Balev M, Ding Q, Heller B, Ploss A. Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus. Elife. 2019 ;8.
Pereira TD, Aldarondo DE, Willmore L, Kislin M, Wang SS-H, Murthy M, et al. Fast animal pose estimation using deep neural networks. Nat Methods. 2019 ;16(1):117-125.
Federspiel JD, Greco TM, Lum KK, Cristea IM. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Mol Cell Proteomics. 2019 ;18(8 suppl 1):S92-S113.
Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. 2019 ;567(7749):535-539.
Berger S, Pho H, Fleury-Curado T, Bevans-Fonti S, Younas H, Shin M-K, et al. Intranasal Leptin Relieves Sleep-disordered Breathing in Mice with Diet-induced Obesity. Am J Respir Crit Care Med. 2019 ;199(6):773-783.