Publications
Automated high-throughput mouse transsynaptic viral tracing using iDISCO+ tissue clearing, light-sheet microscopy, and BrainPipe. STAR Protoc. 2022 ;3(2):101289.
. Bidirectional communication in oogenesis: a dynamic conversation in mice and Drosophila. Trends Cell Biol. 2022 ;32(4):311-323.
. Circulating metabolite homeostasis achieved through mass action. Nat Metab. 2022 ;4(1):141-152.
. Deep phenotyping reveals movement phenotypes in mouse neurodevelopmental models. Mol Autism. 2022 ;13(1):12.
. Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease. Cell Syst. 2022 ;13(4):304-320.e5.
. A Flexible Platform for Monitoring Cerebellum-Dependent Sensory Associative Learning. J Vis Exp. 2022 ;(179).
. GCN2 adapts protein synthesis to scavenging-dependent growth. Cell Syst. 2022 ;13(2):158-172.e9.
. Generation and characterization of genetically and antigenically diverse infectious clones of dengue virus serotypes 1-4. Emerg Microbes Infect. 2022 ;11(1):227-239.
. Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection. Cell Rep. 2022 ;39(3):110714.
. Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate. Proc Natl Acad Sci U S A. 2022 ;119(11):e2112008119.
. Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth. Med (N Y). 2022 ;3(2):119-136.
. MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function. Immunity. 2022 ;55(1):65-81.e9.
. SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma. Blood. 2022 ;139(4):538-553.
. SLEAP: A deep learning system for multi-animal pose tracking. Nat Methods. 2022 ;19(4):486-495.
. Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis. Nat Cancer. 2022 ;3(1):43-59.
. Transmural pressure signals through retinoic acid to regulate lung branching. Development. 2022 ;149(2).
. μMap-Red: Proximity Labeling by Red Light Photocatalysis. J Am Chem Soc. 2022 ;144(14):6154-6162.
. The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine. Cell Metab. 2021 ;33(5):905-922.e6.
. Animal Models of Hepatitis B Virus Infection-Success, Challenges, and Future Directions. Viruses. 2021 ;13(5).
. Bicc1 and Dicer regulate left-right patterning through post-transcriptional control of the Nodal inhibitor Dand5. Nat Commun. 2021 ;12(1):5482.
. CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production. Cells. 2021 ;10(9).
. Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation. Dev Cell. 2021 ;56(21):3019-3034.e7.
. Celsr1 adhesive interactions mediate the asymmetric organization of planar polarity complexes. Elife. 2021 ;10.
. Dll1 quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway. Nat Commun. 2021 ;12(1):432.
. Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development. J Clin Invest. 2021 ;131(1).
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