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Zhang Y, Xu Y, Lu W, Li J, Yu S, Brown EJ, et al. G6PD-mediated increase in de novo NADP biosynthesis promotes antioxidant defense and tumor metastasis. Sci Adv. 2022 ;8(29):eabo0404.
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Yang L, TeSlaa T, Ng S, Nofal M, Wang L, Lan T, et al. Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth. Med (N Y). 2022 ;3(2):119-136.
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Wong C, Tang LH, Davidson C, Vosburgh E, Chen W, Foran DJ, et al. Two well-differentiated pancreatic neuroendocrine tumor mouse models. Cell Death Differ. 2020 ;27(1):269-283.
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Schild T, McReynolds MR, Shea C, Low V, Schaffer BE, Asara JM, et al. NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma. Cell Rep. 2021 ;35(11):109238.
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Rajeshkumar NV, Yabuuchi S, Pai SG, De Oliveira E, Kamphorst JJ, Rabinowitz JD, et al. Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin. Clin Cancer Res. 2017 ;23(18):5639-5647.
P
Phan T, Nguyen VH, Buettner R, Morales C, Yang L, Wong P, et al. Inhibition of pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer. Int J Biol Sci. 2021 ;17(9):2240-2251.
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Nofal M, Wang T, Yang L, Jankowski CSR, Li SHsin-Jung, Han S, et al. GCN2 adapts protein synthesis to scavenging-dependent growth. Cell Syst. 2022 ;13(2):158-172.e9.
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Lee E, Kang Y. Lineage tracing reveals metastatic dynamics. Cancer Cell. 2021 ;39(8):1050-1052.
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Hui S, Ghergurovich JM, Morscher RJ, Jang C, Teng X, Lu W, et al. Glucose feeds the TCA cycle via circulating lactate. Nature. 2017 ;551(7678):115-118.
D
Davidson SM, Jonas O, Keibler MA, Hou HWei, Luengo A, Mayers JR, et al. Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors. Nat Med. 2017 ;23(2):235-241.