Publications
Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding. Cell. 2022 ;185(7):1143-1156.e13.
. The sacrificial adaptor protein Skp functions to remove stalled substrates from the β-barrel assembly machine. Proc Natl Acad Sci U S A. 2022 ;119(1).
. Chaperoning SNARE Folding and Assembly. Annu Rev Biochem. 2021 ;90:581-603.
. Structural basis for sterol sensing by Scap and Insig. Cell Rep. 2021 ;35(13):109299.
. Functions of the BamBCDE Lipoproteins Revealed by Bypass Mutations in BamA. J Bacteriol. 2020 ;202(21).
. Structural and functional diversity calls for a new classification of ABC transporters. FEBS Lett. 2020 ;594(23):3767-3775.
. Outer Membrane Protein Insertion by the β-barrel Assembly Machine. EcoSal Plus. 2019 ;8(2).
. Are natural proteins special? Can we do that?. Curr Opin Struct Biol. 2018 ;48:124-132.
. An Atypical Mechanism of Split Intein Molecular Recognition and Folding. J Am Chem Soc. 2018 ;140(37):11791-11799.
. A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli. Nat Chem Biol. 2018 ;14(3):253-255.
. Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion. Proc Natl Acad Sci U S A. 2018 ;115(10):2359-2364.
. Characterization of a stalled complex on the β-barrel assembly machine. Proc Natl Acad Sci U S A. 2016 ;113(31):8717-22.
. Classifying β-Barrel Assembly Substrates by Manipulating Essential Bam Complex Members. J Bacteriol. 2016 ;198(14):1984-92.
. . Structure and mechanism of the uracil transporter UraA. Nature. 2011 ;472(7342):243-6.
. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science. 2009 ;323(5922):1693-7.
. Protein reconstitution and three-dimensional domain swapping: benefits and constraints of covalency. Protein Sci. 2007 ;16(11):2317-33.
. WrbA bridges bacterial flavodoxins and eukaryotic NAD(P)H:quinone oxidoreductases. Protein Sci. 2007 ;16(10):2301-5.
. Regulation of LuxPQ receptor activity by the quorum-sensing signal autoinducer-2. Mol Cell. 2005 ;18(5):507-18.
. Globularity and protein function. J Biomol Struct Dyn. 2000 ;17 Suppl 1:87-8.
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