Variability in chest compression rate calculations during pediatric cardiopulmonary resuscitation. Author William Landis, Ryan Morgan, Ron Reeder, Kathryn Graham, Ashley Siems, J Wesley Diddle, Murray Pollack, Tensing Maa, Richard Fernandez, Andrew Yates, Bradley Tilford, Tageldin Ahmed, Kathleen Meert, Carleen Schneiter, Robert Bishop, Peter Mourani, Maryam Naim, Stuart Friess, Candice Burns, Arushi Manga, Deborah Franzon, Sarah Tabbutt, Patrick McQuillen, Christopher Horvat, Matthew Bochkoris, Joseph Carcillo, Leanna Huard, Myke Federman, Anil Sapru, Shirley Viteri, David Hehir, Daniel Notterman, Richard Holubkov, J Michael Dean, Vinay Nadkarni, Robert Berg, Heather Wolfe, Robert Sutton, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators the National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators Publication Year 2020 Type Journal Article Abstract AIM: The mathematical method used to calculate chest compression (CC) rate during cardiopulmonary resuscitation varies in the literature and across device manufacturers. The objective of this study was to determine the variability in calculated CC rates by applying four published methods to the same dataset.METHODS: This study was a secondary investigation of the first 200 pediatric cardiac arrest events with invasive arterial line waveform data in the ICU-RESUScitation Project (NCT02837497). Instantaneous CC rates were calculated during periods of uninterrupted CCs. The defined minimum interruption length affects rate calculation (e.g., if an interruption is defined as a break in CCs ≥ 2 s, the lowest possible calculated rate is 30 CCs/min). Average rates were calculated by four methods: 1) rate with an interruption defined as ≥ 1 s; 2) interruption ≥ 2 s; 3) interruption ≥ 3 s; 4) method #3 excluding top and bottom quartiles of calculated rates. American Heart Association Guideline-compliant rate was defined as 100-120 CCs/min. A clinically important change was defined as ±5 CCs/min. The percentage of events and epochs (30 s periods) that changed Guideline-compliant status was calculated.RESULTS: Across calculation methods, mean CC rates (118.7-119.5/min) were similar. Comparing all methods, 14 events (7%) and 114 epochs (6%) changed Guideline-compliant status.CONCLUSION: Using four published methods for calculating CC rate, average rates were similar, but 7% of events changed Guideline-compliant status. These data suggest that a uniform calculation method (interruption ≥ 1 s) should be adopted to decrease variability in resuscitation science. Keywords Humans, Child, Pressure, Research Design, Cardiopulmonary Resuscitation, Heart Arrest, American Heart Association Journal Resuscitation Volume 149 Pages 127-133 Date Published 2020 Apr ISSN Number 1873-1570 DOI 10.1016/j.resuscitation.2020.01.040 Alternate Journal Resuscitation PMCID PMC7296394 PMID 32088254 PubMedPubMed CentralGoogle ScholarBibTeXEndNote X3 XML