| Title | The round trip model for severe herpes zoster caused by live attenuated varicella vaccine virus. |
| Publication Type | Journal Article |
| Year of Publication | 2020 |
| Authors | Grose, C, Enquist, LW |
| Journal | J Med Virol |
| Volume | 92 |
| Issue | 8 |
| Pagination | 938-940 |
| Date Published | 2020 Aug |
| ISSN | 1096-9071 |
| Keywords | Animals, Axons, Chickenpox Vaccine, Child, Child, Preschool, Ganglia, Spinal, Herpes Zoster, Herpesvirus 3, Human, Humans, Infant, Models, Biological, Sensory Receptor Cells, Skin, Vaccines, Attenuated, Virus Activation, Virus Latency, Virus Replication |
| Abstract | <p>Varicella vaccine is a live attenuated varicella‐zoster virus. Varicella vaccine can enter latency and later reactivate as herpes zoster. Pseudorabies virus is another herpesvirus closely related to varicella‐zoster virus. The round trip model for pseudorabies virus explains pathogenesis of herpes zoster from vaccine virus.</p> |
| DOI | 10.1002/jmv.25664 |
| Alternate Journal | J Med Virol |
| PubMed ID | 31943220 |
| PubMed Central ID | PMC7354881 |
| Grant List | R01 HL126667 / HL / NHLBI NIH HHS / United States R37 NS033506 / NS / NINDS NIH HHS / United States HL126667 / NH / NIH HHS / United States |
