| Title | RAI2: Linking Retinoic Acid Signaling with Metastasis Suppression. |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Esposito, M, Kang, Y |
| Journal | Cancer Discov |
| Volume | 5 |
| Issue | 5 |
| Pagination | 466-8 |
| Date Published | 2015 May |
| ISSN | 2159-8290 |
| Keywords | Bone Marrow, Breast Neoplasms, Female, Humans, Intercellular Signaling Peptides and Proteins, Neoplastic Cells, Circulating, Proteins |
| Abstract | <p>Considerable evidence points to the importance of disseminated tumor cells, which are commonly detected in the bone marrow and display features of cellular plasticity, in predicting the clinical outcome of breast cancer. In this issue of Cancer Discovery, Werner and colleagues report on the discovery of retinoic acid-induced 2 (RAI2) as a differentiation factor that suppresses early metastatic spread of estrogen receptor-positive breast cancer.</p> |
| DOI | 10.1158/2159-8290.CD-15-0352 |
| Alternate Journal | Cancer Discov |
| PubMed ID | 25941336 |
| PubMed Central ID | PMC4422076 |
| Grant List | F31 CA192461 / CA / NCI NIH HHS / United States R01 CA141062 / CA / NCI NIH HHS / United States R01CA141062 / CA / NCI NIH HHS / United States |
