| Title | pSTAT3 Reactive Astrocytes Promote Brain Metastasis. |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Shen, M, Kang, Y |
| Journal | Trends Mol Med |
| Volume | 24 |
| Issue | 9 |
| Pagination | 733-735 |
| Date Published | 2018 09 |
| ISSN | 1471-499X |
| Keywords | Astrocytes, Brain, Brain Neoplasms, Humans, STAT3 Transcription Factor, Stromal Cells, Tumor Microenvironment |
| Abstract | <p>The tumor microenvironment contains heterogeneous populations of stromal cells with important roles in cancer progression and metastasis. In a recent study published in Nature Medicine, pSTAT3 reactive astrocytes were found to promote brain metastasis by altering the tumor microenvironment, and represent a promising target for the treatment of brain metastasis.</p> |
| DOI | 10.1016/j.molmed.2018.07.002 |
| Alternate Journal | Trends Mol Med |
| PubMed ID | 30029985 |
