Prime Editing: Precision Genome Editing by Reverse Transcription.

Author
Jun Yan, Ann Cirincione, Britt Adamson
Publication Year
2020

Type

Journal Article
Abstract

Genome editing is a method for making targeted sequence changes to the genomes of living cells. Prime editing, recently reported by Anzalone et al. (2019), is a new technology that uses reverse transcription to "write" programmed sequence changes into genomic DNA and thus promises significant technical advances.

Keywords
DNA, Reverse Transcription, Genome, Gene Editing
Journal
Mol Cell
Volume
77
Issue
2
Pages
210-212
Date Published
2020 Jan 16
ISSN Number
1097-4164
DOI
10.1016/j.molcel.2019.12.016
Alternate Journal
Mol Cell
PMID
31951546