Title | Prime Editing: Precision Genome Editing by Reverse Transcription. |
Publication Type | Journal Article |
Year of Publication | 2020 |
Authors | Yan, J, Cirincione, A, Adamson, B |
Journal | Mol Cell |
Volume | 77 |
Issue | 2 |
Pagination | 210-212 |
Date Published | 2020 01 16 |
ISSN | 1097-4164 |
Keywords | DNA, Gene Editing, Genome, Reverse Transcription |
Abstract | <p>Genome editing is a method for making targeted sequence changes to the genomes of living cells. Prime editing, recently reported by Anzalone et al. (2019), is a new technology that uses reverse transcription to "write" programmed sequence changes into genomic DNA and thus promises significant technical advances.</p> |
DOI | 10.1016/j.molcel.2019.12.016 |
Alternate Journal | Mol Cell |
PubMed ID | 31951546 |
Grant List | T32 HG003284 / HG / NHGRI NIH HHS / United States |