Prime Editing: Precision Genome Editing by Reverse Transcription.

TitlePrime Editing: Precision Genome Editing by Reverse Transcription.
Publication TypeJournal Article
Year of Publication2020
AuthorsYan, J, Cirincione, A, Adamson, B
JournalMol Cell
Volume77
Issue2
Pagination210-212
Date Published2020 Jan 16
ISSN1097-4164
Abstract

Genome editing is a method for making targeted sequence changes to the genomes of living cells. Prime editing, recently reported by Anzalone et al. (2019), is a new technology that uses reverse transcription to "write" programmed sequence changes into genomic DNA and thus promises significant technical advances.

DOI10.1016/j.molcel.2019.12.016
Alternate JournalMol. Cell
PubMed ID31951546