Title | A PBX/MEIS Complex Balances Reproduction and Somatic Resilience. |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Heimbucher, T, Murphy, CT |
Journal | Dev Cell |
Volume | 49 |
Issue | 2 |
Pagination | 157-158 |
Date Published | 2019 Apr 22 |
ISSN | 1878-1551 |
Keywords | Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Homeodomain Proteins, Transcription Factors |
Abstract | <p>Resource reallocation to metabolic processes promoting reproduction is critical for the survival of a species and therefore is tightly regulated. In this issue of Developmental Cell, Dowen (2019) finds that a PBX/MEIS homeodomain transcription factor complex controls a transcriptional network that balances reproduction versus longevity and somatic maintenance.</p> |
DOI | 10.1016/j.devcel.2019.04.005 |
Alternate Journal | Dev Cell |
PubMed ID | 31014476 |
PubMed Central ID | PMC7452753 |
Grant List | R56 AG047344 / AG / NIA NIH HHS / United States |