New vaccines: challenges of discovery.

TitleNew vaccines: challenges of discovery.
Publication TypeJournal Article
Year of Publication2016
AuthorsMahmoud, A
JournalMicrob Biotechnol
Volume9
Issue5
Pagination549-52
Date Published2016 09
ISSN1751-7915
KeywordsAnimals, Communicable Diseases, Disease Transmission, Infectious, Drug Discovery, Humans, Vaccines
Abstract

<p>Vaccines have been a major component of preventing and controlling infectious diseases. The basis for discovery of what protects is reviewed as well as new attempts in utilizing Reverse Vaccinology, RNA-RNA methods and proteome analysis are adding significantly to our knowledge. The challenge of how to define protective and defined components of microbes is still hampering efforts to discover new vaccines. Recent excitement about immunotherapy of cancer opens the way to develop vaccines against multiple malignancies.</p>

DOI10.1111/1751-7915.12397
Alternate JournalMicrob Biotechnol
PubMed ID27534704
PubMed Central IDPMC4993171