| Title | A new cap for kinetochore fibre minus ends. |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Petry, S, Vale, RD |
| Journal | Nat Cell Biol |
| Volume | 13 |
| Issue | 12 |
| Pagination | 1389-91 |
| Date Published | 2011 Nov 13 |
| ISSN | 1476-4679 |
| Keywords | Animals, Chromosome Segregation, Humans, Kinetochores, Nuclear Proteins, ran GTP-Binding Protein, RNA-Binding Proteins, Spindle Apparatus |
| Abstract | <p>In mitotic spindles, each sister chromatid is directly attached to a spindle pole through microtubule bundles known as kinetochore fibres. Microspherule protein 1 (MCRS1) is now shown to support spindle assembly by localizing to the minus ends of kinetochore fibres and protecting them from depolymerization.</p> |
| DOI | 10.1038/ncb2387 |
| Alternate Journal | Nat. Cell Biol. |
| PubMed ID | 22081093 |
| PubMed Central ID | PMC3532025 |
| Grant List | / / Howard Hughes Medical Institute / United States K99 GM100013 / GM / NIGMS NIH HHS / United States R01 GM038499 / GM / NIGMS NIH HHS / United States |
