Neural underpinnings of the evidence accumulator. Author Carlos Brody, Timothy Hanks Publication Year 2016 Type Journal Article Abstract Gradual accumulation of evidence favoring one or another choice is considered a core component of many different types of decisions, and has been the subject of many neurophysiological studies in non-human primates. But its neural circuit mechanisms remain mysterious. Investigating it in rodents has recently become possible, facilitating perturbation experiments to delineate the relevant causal circuit, as well as the application of other tools more readily available in rodents. In addition, advances in stimulus design and analysis have aided studying the relevant neural encoding. In complement to ongoing non-human primate studies, these newly available model systems and tools place the field at an exciting time that suggests that the dynamical circuit mechanisms underlying accumulation of evidence could soon be revealed. Keywords Animals, Models, Animal, Choice Behavior, Neurophysiology, Rodentia Journal Curr Opin Neurobiol Volume 37 Pages 149-157 Date Published 2016 Apr ISSN Number 1873-6882 DOI 10.1016/j.conb.2016.01.003 Alternate Journal Curr Opin Neurobiol PMCID PMC5777584 PMID 26878969 PubMedPubMed CentralGoogle ScholarBibTeXEndNote X3 XML