|Title||A multifaceted signal recorder of cellular experiences using Cas12a base-editing.|
|Publication Type||Journal Article|
|Year of Publication||2022|
|Authors||Zhang, P, Chan, MM|
Technological advances have led to the emergence of lineage tracers, but signal recorders for mammalian systems have remained elusive. Kempton et al. have developed a Cas12a base-editing signal recorder capable of capturing diverse signals and operating in various experimental designs. The recorder enables new opportunities to chronicle cellular history.
|Alternate Journal||Trends Biotechnol|