| Title | Microbial metabolite as icebreaker for immunotherapy. |
| Publication Type | Journal Article |
| Year of Publication | 2022 |
| Authors | Tang, Y, Kang, Y |
| Journal | Cell Metab |
| Volume | 34 |
| Issue | 4 |
| Pagination | 506-507 |
| Date Published | 2022 Apr 05 |
| ISSN | 1932-7420 |
| Keywords | Humans, Immunity, Cellular, Immunotherapy, Triple Negative Breast Neoplasms |
| Abstract | <p>Immunotherapy has limited success in triple-negative breast cancer (TNBC). In this issue of Cell Metabolism, Wang et al. found that microbial metabolite TMAO boosts CD8 T cell-mediated antitumor immunity by inducing pyroptosis in tumor cells, enhancing the efficacy of immunotherapy in TNBC (Wang et al., 2022).</p> |
| DOI | 10.1016/j.cmet.2022.03.003 |
| Alternate Journal | Cell Metab |
| PubMed ID | 35385701 |
