LuxS quorum sensing: more than just a numbers game. Author Karina Xavier, Bonnie Bassler Publication Year 2003 Type Journal Article Abstract Quorum sensing is a process of bacterial cell-to-cell communication involving the production and detection of extracellular signaling molecules called autoinducers. Quorum sensing allows populations of bacteria to collectively control gene expression, and thus synchronize group behavior. Processes controlled by quorum sensing are typically ones that are unproductive unless many bacteria act together. Most autoinducers enable intraspecies communication; however, a recently discovered autoinducer AI-2 has been proposed to serve as a 'universal signal' for interspecies communication. Studies suggest that AI-2 encodes information in addition to specifics about cell number. Keywords Gene Expression Regulation, Bacterial, Bacterial Proteins, Models, Biological, Bacterial Physiological Phenomena, Signal Transduction, Lactones, Bacteria, Models, Molecular, Homoserine, Carbon-Sulfur Lyases Journal Curr Opin Microbiol Volume 6 Issue 2 Pages 191-7 Date Published 2003 Apr ISSN Number 1369-5274 DOI 10.1016/s1369-5274(03)00028-6 Alternate Journal Curr Opin Microbiol PMID 12732311 PubMedGoogle ScholarBibTeXEndNote X3 XML