Lipid Metabolism Fuels Cancer's Spread.

TitleLipid Metabolism Fuels Cancer's Spread.
Publication TypeJournal Article
Year of Publication2017
AuthorsLi, Z, Kang, Y
JournalCell Metab
Volume25
Issue2
Pagination228-230
Date Published2017 02 07
ISSN1932-7420
KeywordsCarrier Proteins, Fatty Acids, Humans, Lipid Metabolism, Neoplasms
Abstract

<p>The ability to prospectively identify metastasis-initiating cells is essential for developing new anti-metastasis therapeutics. In a recent issue of Nature, Pascual et al. (2017) demonstrate that the fatty acid receptor CD36 marks a subpopulation of cancer cells with unique metastasis-initiating potential, highlighting a key role of lipid metabolism in metastatic colonization.</p>

DOI10.1016/j.cmet.2017.01.016
Alternate JournalCell Metab.
PubMed ID28178563