| Title | Lineage tracing reveals metastatic dynamics. |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | Lee, E, Kang, Y |
| Journal | Cancer Cell |
| Volume | 39 |
| Issue | 8 |
| Pagination | 1050-1052 |
| Date Published | 2021 08 09 |
| ISSN | 1878-3686 |
| Keywords | Cell Lineage, Humans, Pancreatic Neoplasms, Sequence Analysis, RNA, Whole Exome Sequencing |
| Abstract | <p>Combining single-cell lineage tracing with RNA sequencing has provided unprecedented opportunities to prospectively explore metastatic dynamics in vivo. In this issue of Cancer Cell, Simeonov et al. developed the macsGESTALT lineage recording system to reveal that hybrid EMT states and S100 expression are associated with elevated metastatic abilities in a pancreatic cancer model.</p> |
| DOI | 10.1016/j.ccell.2021.06.005 |
| Alternate Journal | Cancer Cell |
| PubMed ID | 34171265 |
