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Virulence Factors

  • 1.
    Taylor I, Murray-Nerger L, Greco T, Liu D, Cristea I, Bassler B. Protein Interaction Networks of Catalytically Active and Catalytically Inactive PqsE in Pseudomonas aeruginosa. mBio. 2022;13(5):e0155922. PMCID: PMC9600345
    Reference Link
  • 1.
    Scheffler R, Bratton B, Gitai Z. Pseudomonas aeruginosa clinical blood isolates display significant phenotypic variability. PLoS One. 2022;17(7):e0270576. PMCID: PMC9258867
    Reference Link
  • 1.
    Høyland-Kroghsbo N, Bassler B. Phage Infection Restores PQS Signaling and Enhances Growth of a Pseudomonas aeruginosa Quorum-Sensing Mutant. J Bacteriol. 2022;204(5):e0055721. PMCID: PMC9112912
    Reference Link
  • 1.
    Simanek K, Taylor I, Richael E, Lasek-Nesselquist E, Bassler B, Paczkowski J. The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in . Microbiol Spectr. 2022;10(1):e0210821. PMCID: PMC8754118
    Reference Link
  • 1.
    Behnke M, Khan A, Lauron E, Jimah J, Wang Q, Tolia N, Sibley D. Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii. PLoS Genet. 2015;11(8):e1005434. PMCID: PMC4546408
    Reference Link
  • 1.
    Jimah J, Salinas N, Sala-Rabanal M, Jones N, Sibley D, Nichols C, Schlesinger P, Tolia N. Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption. Elife. 2016;5. PMCID: PMC5132341
    Reference Link
  • 1.
    Li A, Okada B, Rosen P, Seyedsayamdost M. Piperacillin triggers virulence factor biosynthesis via the oxidative stress response in . Proc Natl Acad Sci U S A. 2021;118(26). PMCID: PMC8256049
    Reference Link
  • 1.
    Taylor I, Paczkowski J, Jeffrey P, Henke B, Smith C, Bassler B. Inhibitor Mimetic Mutations in the PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production. ACS Chem Biol. 2021;16(4):740–752. PMCID: PMC8056388
    Reference Link
  • 1.
    Vrla G, Esposito M, Zhang C, Kang Y, Seyedsayamdost M, Gitai Z. Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa. PLoS Pathog. 2020;16(9):e1008867. PMCID: PMC7515202
    Reference Link
  • 1.
    Li A, Mao D, Yoshimura A, Rosen P, Martin L, Gallant Étienne, Wühr M, Seyedsayamdost M. Multi-Omic Analyses Provide Links between Low-Dose Antibiotic Treatment and Induction of Secondary Metabolism in Burkholderia thailandensis. mBio. 2020;11(1). PMCID: PMC7042699
    Reference Link
  • 1.
    Okada B, Li A, Seyedsayamdost M. Identification of the Hypertension Drug Guanfacine as an Antivirulence Agent in Pseudomonas aeruginosa. Chembiochem. 2019;20(15):2005–2011. PMCID: PMC6814388
    Reference Link
  • 1.
    Klaus J, Deay J, Neuenswander B, Hursh W, Gao Z, Bouddhara T, Williams T, Douglas J, Monize K, Martins P, Majerczyk C, Seyedsayamdost M, Peterson B, Rivera M, Chandler J. Malleilactone Is a Burkholderia pseudomallei Virulence Factor Regulated by Antibiotics and Quorum Sensing. J Bacteriol. 2018;200(14). PMCID: PMC6018353
    Reference Link
  • 1.
    Deng D, Yan C, Pan X, Mahfouz M, Wang J, Zhu J-K, Shi Y, Yan N. Structural basis for sequence-specific recognition of DNA by TAL effectors. Science. 2012;335(6069):720–3. PMCID: PMC3586824
    Reference Link
  • 1.
    Chahal J, Gallagher C, DeHart C, Flint S. The repression domain of the E1B 55-kilodalton protein participates in countering interferon-induced inhibition of adenovirus replication. J Virol. 2013;87(8):4432–44. PMCID: PMC3624377
    Reference Link
  • 1.
    Persat A, Inclan Y, Engel J, Stone H, Gitai Z. Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2015;112(24):7563–8. PMCID: PMC4475988
    Reference Link
  • 1.
    Rutherford S, Bassler B. Bacterial quorum sensing: its role in virulence and possibilities for its control. Cold Spring Harb Perspect Med. 2012;2(11). PMCID: PMC3543102
    Reference Link

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