1.Hansen J, Sealfon R, Menon R, Eadon M, Lake B, Steck B, Anjani K, Parikh S, Sigdel T, Zhang G, Velickovic D, Barwinska D, Alexandrov T, Dobi D, Rashmi P, Otto E, Rivera M, Rose M, Anderton C, Shapiro J, Pamreddy A, Winfree S, Xiong Y, He Y, de Boer I, Hodgin J, Barisoni L, Naik A, Sharma K, Sarwal M, Zhang K, Himmelfarb J, Rovin B, El-Achkar T, Laszik Z, He J, Dagher P, Valerius T, Jain S, Satlin L, Troyanskaya O, Kretzler M, Iyengar R, Azeloglu E, Kidney Precision Medicine Project. A reference tissue atlas for the human kidney. Sci Adv. 2022;8(23):eabn4965. PMCID: PMC9176741 Reference Link
1.Chen X, Du Y, Broussard G, Kislin M, Yuede C, Zhang S, Dietmann S, Gabel H, Zhao G, Wang S, Zhang X, Bonni A. Transcriptomic mapping uncovers Purkinje neuron plasticity driving learning. Nature. 2022;605(7911):722–727. PMCID: PMC9887520 Reference Link
1.Zhang Z, Zamojski M, Smith G, Willis T, Yianni V, Mendelev N, Pincas H, Seenarine N, Amper M, Vasoya M, Cheng W, Zaslavsky E, Nair V, Turgeon J, Bernard D, Troyanskaya O, Andoniadou C, Sealfon S, Ruf-Zamojski F. Single nucleus transcriptome and chromatin accessibility of postmortem human pituitaries reveal diverse stem cell regulatory mechanisms. Cell Rep. 2022;38(10):110467. PMCID: PMC8957708 Reference Link
1.Kleiner R. Interrogating the transcriptome with metabolically incorporated ribonucleosides. Mol Omics. 2021;17(6):833–841. PMCID: PMC8648987 Reference Link
1.Lindström N, Sealfon R, Chen X, Parvez R, Ransick A, Brandine G, Guo J, Hill B, Tran T, Kim A, Zhou J, Tadych A, Watters A, Wong A, Lovero E, Grubbs B, Thornton M, McMahon J, Smith A, Ruffins S, Armit C, Troyanskaya O, McMahon A. Spatial transcriptional mapping of the human nephrogenic program. Dev Cell. 2021;56(16):2381–2398.e6. PMCID: PMC8396064 Reference Link
1.Quinn J, Jones M, Okimoto R, Nanjo S, Chan M, Yosef N, Bivona T, Weissman J. Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts. Science. 2021;371(6532). PMCID: PMC7983364 Reference Link
1.Ruf-Zamojski F, Zhang Z, Zamojski M, Smith G, Mendelev N, Liu H, Nudelman G, Moriwaki M, Pincas H, Castanon R, Nair V, Seenarine N, Amper M, Zhou X, Ongaro L, Toufaily C, Schang G, Nery J, Bartlett A, Aldridge A, Jain N, Childs G, Troyanskaya O, Ecker J, Turgeon J, Welt C, Bernard D, Sealfon S. Single nucleus multi-omics regulatory landscape of the murine pituitary. Nat Commun. 2021;12(1):2677. PMCID: PMC8113460 Reference Link
1.Goodwin K, Nelson C. Uncovering cellular networks in branching morphogenesis using single-cell transcriptomics. Curr Top Dev Biol. 2021;143:239–280. PMID: 33820623 Reference Link
1.Ledo J, Zhang R, Mesin L, Mourão-Sá D, Azevedo E, Troyanskaya O, Bustos V, Greengard P. Lack of a site-specific phosphorylation of Presenilin 1 disrupts microglial gene networks and progenitors during development. PLoS One. 2020;15(8):e0237773. PMCID: PMC7444478 Reference Link
1.Cao W, Kabelitz S, Gupta M, Yeung E, Lin S, Rammelt C, Ihling C, Pekovic F, Low T, Siddiqui N, Cheng M, Angers S, Smibert C, Wühr M, Wahle E, Lipshitz H. Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cell Rep. 2020;31(12):107783. PMCID: PMC7372737 Reference Link
1.Roussarie J-P, Yao V, Rodriguez-Rodriguez P, Oughtred R, Rust J, Plautz Z, Kasturia S, Albornoz C, Wang W, Schmidt E, Dannenfelser R, Tadych A, Brichta L, Barnea-Cramer A, Heintz N, Hof P, Heiman M, Dolinski K, Flajolet M, Troyanskaya O, Greengard P. Selective Neuronal Vulnerability in Alzheimer’s Disease: A Network-Based Analysis. Neuron. 2020;107(5):821–835.e12. PMCID: PMC7580783 Reference Link
1.Replogle J, Norman T, Xu A, Hussmann J, Chen J, Cogan Z, Meer E, Terry J, Riordan D, Srinivas N, Fiddes I, Arthur J, Alvarado L, Pfeiffer K, Mikkelsen T, Weissman J, Adamson B. Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing. Nat Biotechnol. 2020;38(8):954–961. PMCID: PMC7416462 Reference Link
1.Arey R, Kaletsky R, Murphy C. Nervous system-wide profiling of presynaptic mRNAs reveals regulators of associative memory. Sci Rep. 2019;9(1):20314. PMCID: PMC6937282 Reference Link
1.Preston C, Storm E, Burdine R, Bradley T, Uttecht A, Faustino R. Nucleoporin insufficiency disrupts a pluripotent regulatory circuit in a pro-arrhythmogenic stem cell line. Sci Rep. 2019;9(1):12691. PMCID: PMC6722237 Reference Link
1.Zhou J, Schor I, Yao V, Theesfeld C, Marco-Ferreres R, Tadych A, Furlong E, Troyanskaya O. Accurate genome-wide predictions of spatio-temporal gene expression during embryonic development. PLoS Genet. 2019;15(9):e1008382. PMCID: PMC6779412 Reference Link
1.Sanfilippo J, Lorestani A, Koch M, Bratton B, Siryaporn A, Stone H, Gitai Z. Microfluidic-based transcriptomics reveal force-independent bacterial rheosensing. Nat Microbiol. 2019;4(8):1274–1281. PMCID: PMC6656604 Reference Link
1.Federspiel J, Greco T, Lum K, Cristea I. Hdac4 Interactions in Huntington’s Disease Viewed Through the Prism of Multiomics. Mol Cell Proteomics. 2019;18(8 suppl 1):S92-S113. PMCID: PMC6692770 Reference Link
1.Lee Y-S, Krishnan A, Oughtred R, Rust J, Chang C, Ryu J, Kristensen V, Dolinski K, Theesfeld C, Troyanskaya O. A Computational Framework for Genome-wide Characterization of the Human Disease Landscape. Cell Syst. 2019;8(2):152–162.e6. PMCID: PMC7374759 Reference Link
1.Harder J, Menon R, Otto E, Zhou J, Eddy S, Wys N, O’Connor C, Luo J, Nair V, Cebrian C, Spence J, Bitzer M, Troyanskaya O, Hodgin J, Wiggins R, Freedman B, Kretzler M, European Renal cDNA Bank (ERCB), Nephrotic Syndrome Study Network (NEPTUNE). Organoid single cell profiling identifies a transcriptional signature of glomerular disease. JCI Insight. 2019;4(1). PMCID: PMC6485369 Reference Link
1.Douam F, Ziegler C, Hrebikova G, Fant B, Leach R, Parsons L, Wang W, Gaska J, Winer B, Heller B, Shalek A, Ploss A. Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses. Nat Commun. 2018;9(1):5031. PMCID: PMC6262001 Reference Link
1.vonHoldt B, Ji S, Aardema M, Stahler D, Udell M, Sinsheimer J. Activity of Genes with Functions in Human Williams-Beuren Syndrome Is Impacted by Mobile Element Insertions in the Gray Wolf Genome. Genome Biol Evol. 2018;10(6):1546–1553. PMCID: PMC6007319 Reference Link
1.Templeman N, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, Murphy C. Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity. Curr Biol. 2018;28(5):753–760.e4. PMCID: PMC5893159 Reference Link
1.Wilson M, Ravindran P, Lim W, Toettcher J. Tracing Information Flow from Erk to Target Gene Induction Reveals Mechanisms of Dynamic and Combinatorial Control. Mol Cell. 2017;67(5):757–769.e5. PMCID: PMC5591080 Reference Link
1.Gong Y, Cao R, Ding G, Hong S, Zhou W, Lu W, Damle M, Fang B, Wang C, Qian J, Lie N, Lanzillotta C, Rabinowitz J, Sun Z. Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle. Mol Cell Endocrinol. 2018;471:22–32. PMCID: PMC5702591 Reference Link
1.Tate A, Andolfatto P, Demuth J, Graham A. The within-host dynamics of infection in trans-generationally primed flour beetles. Mol Ecol. 2017;26(14):3794–3807. PMCID: PMC5653231 Reference Link
1.Gorenshteyn D, Zaslavsky E, Fribourg M, Park C, Wong A, Tadych A, Hartmann B, Albrecht R, García-Sastre A, Kleinstein S, Troyanskaya O, Sealfon S. Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases. Immunity. 2015;43(3):605–14. PMCID: PMC4753773 Reference Link
1.Matthews B, McBride C, DeGennaro M, Despo O, Vosshall L. The neurotranscriptome of the Aedes aegypti mosquito. BMC Genomics. 2016;17:32. PMCID: PMC4704297 Reference Link
1.Kaletsky R, Lakhina V, Arey R, Williams A, Landis J, Ashraf J, Murphy C. The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators. Nature. 2016;529(7584):92–6. PMCID: PMC4708089 Reference Link