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Signal Transduction

  • 1.
    Menon T, Burdine R. A twist in Pitx2 regulation of gut looping. Dev Cell. 2022;57(21):2445–2446. PMID: 36347237
    Reference Link
  • 1.
    McFann S, Shvartsman S, Toettcher J. Putting in the Erk: Growth factor signaling and mesoderm morphogenesis. Curr Top Dev Biol. 2022;149:263–310. PMID: 35606058
    Reference Link
  • 1.
    Bridges A, Prentice J, Wingreen N, Bassler B. Signal Transduction Network Principles Underlying Bacterial Collective Behaviors. Annu Rev Microbiol. 2022;76:235–257. PMCID: PMC9463083
    Reference Link
  • 1.
    McNamara H, Ramm B, Toettcher J. Synthetic developmental biology: New tools to deconstruct and rebuild developmental systems. Semin Cell Dev Biol. 2023;141:33–42. PMID: 35484026
    Reference Link
  • 1.
    Bridges A, Prentice J, Fei C, Wingreen N, Bassler B. Quantitative input-output dynamics of a c-di-GMP signal transduction cascade in Vibrio cholerae. PLoS Biol. 2022;20(3):e3001585. PMCID: PMC8967002
    Reference Link
  • 1.
    Meng J, Jiang Y-Z, Zhao S, Tao Y, Zhang T, Wang X, Zhang Y, Sun K, Yuan M, Chen J, Wei Y, Lan X, Chen M, David C, Chang Z, Guo X, Pan D, Chen M, Shao Z-M, Kang Y, Zheng H. Tumor-derived Jagged1 promotes cancer progression through immune evasion. Cell Rep. 2022;38(10):110492. PMID: 35263601
    Reference Link
  • 1.
    Weaver C, Patel A, Shvartsman S, Levine M, Treen N. ERK signaling dissolves ERF repression condensates in living embryos. Proc Natl Acad Sci U S A. 2022;119(9). PMCID: PMC8892517
    Reference Link
  • 1.
    Jaslove J, Goodwin K, Sundarakrishnan A, Spurlin J, Mao S, Košmrlj A, Nelson C. Transmural pressure signals through retinoic acid to regulate lung branching. Development. 2022;149(2). PMCID: PMC8917413
    Reference Link
  • 1.
    Colonnetta M, Goyal Y, Johnson H, Syal S, Schedl P, Deshpande G. Preformation and epigenesis converge to specify primordial germ cell fate in the early Drosophila embryo. PLoS Genet. 2022;18(1):e1010002. PMCID: PMC8765614
    Reference Link
  • 1.
    Farahani P, Lemke S, Dine E, Uribe G, Toettcher J, Nelson C. Substratum stiffness regulates Erk signaling dynamics through receptor-level control. Cell Rep. 2021;37(13):110181. PMCID: PMC8756379
    Reference Link
  • 1.
    Fang C, Kang Y. E-Cadherin: Context-Dependent Functions of a Quintessential Epithelial Marker in Metastasis. Cancer Res. 2021;81(23):5800–5802. PMID: 34853039
    Reference Link
  • 1.
    Sugiura A, Andrejeva G, Voss K, Heintzman D, Xu X, Madden M, Ye X, Beier K, Chowdhury N, Wolf M, Young A, Greenwood D, Sewell A, Shahi S, Freedman S, Cameron A, Foerch P, Bourne T, García-Cañaveras J, Karijolich J, Newcomb D, Mangalam A, Rabinowitz J, Rathmell J. MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function. Immunity. 2022;55(1):65–81.e9. PMCID: PMC8755618
    Reference Link
  • 1.
    Chitrakar A, Solorio-Kirpichyan K, Prangley E, Rath S, Du J, Korennykh A. Introns encode dsRNAs undetected by RIG-I/MDA5/interferons and sensed via RNase L. Proc Natl Acad Sci U S A. 2021;118(46). PMCID: PMC8609619
    Reference Link
  • 1.
    Ravindran P, McFann S, Thornton R, Toettcher J. A synthetic gene circuit for imaging-free detection of signaling pulses. Cell Syst. 2022;13(2):131–142.e13. PMCID: PMC8857027
    Reference Link
  • 1.
    Elshina E, Velthuis A. The influenza virus RNA polymerase as an innate immune agonist and antagonist. Cell Mol Life Sci. 2021;78(23):7237–7256. PMCID: PMC8532088
    Reference Link
  • 1.
    Brooks J, Behrendt C, Ruhn K, Lee S, Raj P, Takahashi J, Hooper L. The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock. Cell. 2021;184(16):4154–4167.e12. PMCID: PMC8967342
    Reference Link
  • 1.
    Cable J, Pourquié O, Wellen K, Finley L, Aulehla A, Gould A, Teleman A, Tu W, Garrett W, Miguel-Aliaga I, Perrimon N, Hooper L, Walhout A, Wei W, Alexandrov T, Erez A, Ralser M, Rabinowitz J, Hemalatha A, Gutiérrez-Pérez P, Chandel N, Rutter J, Locasale J, Landoni J, Christofk H. Metabolic decisions in development and disease-a Keystone Symposia report. Ann N Y Acad Sci. 2021;1506(1):55–73. PMID: 34414571
    Reference Link
  • 1.
    Verma A, Jena S, Isakov D, Aoki K, Toettcher J, Engelhardt B. A self-exciting point process to study multicellular spatial signaling patterns. Proc Natl Acad Sci U S A. 2021;118(32). PMCID: PMC8364135
    Reference Link
  • 1.
    Baumeister R, Murphy C, Heimbucher T. Metabolic adaptation to hypoxia: do worms and cancer cells share common metabolic responses to hypoxic stress?. Cell Death Differ. 2021;28(4):1434–1436. PMCID: PMC8026991
    Reference Link
  • 1.
    Kumar S, Nandi A, Singh S, Regulapati R, Li N, Tobias J, Siebel C, Blanco M, Klein-Szanto A, Lengner C, Welm A, Kang Y, Chakrabarti R. Dll1 quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway. Nat Commun. 2021;12(1):432. PMCID: PMC7813834
    Reference Link
  • 1.
    Basta L, Hill-Oliva M, Paramore S, Sharan R, Goh A, Biswas A, Cortez M, Little K, Posfai E, Devenport D. New mouse models for high resolution and live imaging of planar cell polarity proteins in vivo. Development. 2021;148(18). PMCID: PMC8487645
    Reference Link
  • 1.
    Dine E, Reed E, Toettcher J. Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch. Cell Rep. 2021;35(12):109280. PMCID: PMC8292983
    Reference Link
  • 1.
    Schild T, McReynolds M, Shea C, Low V, Schaffer B, Asara J, Piskounova E, Dephoure N, Rabinowitz J, Gomes A, Blenis J. NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma. Cell Rep. 2021;35(11):109238. PMID: 34133937
    Reference Link
  • 1.
    Song B, Liu D, Greco T, Cristea I. Post-translational modification control of viral DNA sensors and innate immune signaling. Adv Virus Res. 2021;109:163–199. PMCID: PMC8489191
    Reference Link
  • 1.
    Rabie E, Zhang S, Dunn C, Nelson C. Substratum stiffness signals through integrin-linked kinase and β1-integrin to regulate midbody proteins and abscission during EMT. Mol Biol Cell. 2021;32(18):1664–1676. PMCID: PMC8684726
    Reference Link
  • 1.
    Zhao E, Lalwani M, Chen J-M, Orillac P, Toettcher J, Avalos J. Optogenetic Amplification Circuits for Light-Induced Metabolic Control. ACS Synth Biol. 2021;10(5):1143–1154. PMCID: PMC8721662
    Reference Link
  • 1.
    Valastyan J, Kraml C, Pelczer I, Ferrante T, Bassler B. Saccharomyces cerevisiae Requires To Produce 4-Hydroxy-5-Methylfuran-3(2H)-One, a Mimic of the Bacterial Quorum-Sensing Autoinducer AI-2. mBio. 2021;12(2). PMCID: PMC8092285
    Reference Link
  • 1.
    Cho S, Lee G, Pickering B, Jang C, Park J, He L, Mathur L, Kim S-S, Jung S, Tang H-W, Monette S, Rabinowitz J, Perrimon N, Jaffrey S, Blenis J. mTORC1 promotes cell growth via mA-dependent mRNA degradation. Mol Cell. 2021;81(10):2064–2075.e8. PMCID: PMC8356906
    Reference Link
  • 1.
    Farahani P, Reed E, Underhill E, Aoki K, Toettcher J. Signaling, Deconstructed: Using Optogenetics to Dissect and Direct Information Flow in Biological Systems. Annu Rev Biomed Eng. 2021;23:61–87. PMID: 33722063
    Reference Link
  • 1.
    Eickhoff M, Fei C, Huang X, Bassler B. LuxT controls specific quorum-sensing-regulated behaviors in Vibrionaceae spp. via repression of qrr1, encoding a small regulatory RNA. PLoS Genet. 2021;17(4):e1009336. PMCID: PMC8043402
    Reference Link
  • 1.
    Bridges A, Bassler B. Inverse regulation of biofilm dispersal by polyamine signals. Elife. 2021;10. PMCID: PMC8079147
    Reference Link
  • 1.
    Lee Y, Jung Y, Jeong D-E, Hwang W, Ham S, Park H-E, Kwon S, Ashraf J, Murphy C, Lee S-J. Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop. J Cell Biol. 2021;220(5). PMCID: PMC7941181
    Reference Link
  • 1.
    Garrison C, Schwarzbauer J. Fibronectin fibril alignment is established upon initiation of extracellular matrix assembly. Mol Biol Cell. 2021;32(8):739–752. PMCID: PMC8108514
    Reference Link
  • 1.
    Lum K, Cristea I. Host Innate Immune Response and Viral Immune Evasion During Alphaherpesvirus Infection. Curr Issues Mol Biol. 2021;42:635–686. PMCID: PMC8301600
    Reference Link
  • 1.
    Seath C, Trowbridge A, Muir T, MacMillan D. Reactive intermediates for interactome mapping. Chem Soc Rev. 2021;50(5):2911–2926. PMID: 33458734
    Reference Link
  • 1.
    Minhas P, Latif-Hernandez A, McReynolds M, Durairaj A, Wang Q, Rubin A, Joshi A, He J, Gauba E, Liu L, Wang C, Linde M, Sugiura Y, Moon P, Majeti R, Suematsu M, Mochly-Rosen D, Weissman I, Longo F, Rabinowitz J, Andreasson K. Restoring metabolism of myeloid cells reverses cognitive decline in ageing. Nature. 2021;590(7844):122–128. PMCID: PMC8274816
    Reference Link
  • 1.
    Marmion R, Yang L, Goyal Y, Jindal G, Wetzel J, Singh M, Schüpbach T, Shvartsman S. Molecular mechanisms underlying cellular effects of human MEK1 mutations. Mol Biol Cell. 2021;32(9):974–983. PMCID: PMC8108529
    Reference Link
  • 1.
    Kilinc A, Han S, Barrett L, Anandasivam N, Nelson C. Integrin-linked kinase tunes cell-cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ1. Mol Biol Cell. 2021;32(5):402–412. PMCID: PMC8098849
    Reference Link
  • 1.
    Bridges A, Fei C, Bassler B. Identification of signaling pathways, matrix-digestion enzymes, and motility components controlling biofilm dispersal. Proc Natl Acad Sci U S A. 2020;117(51):32639–32647. PMCID: PMC7768729
    Reference Link
  • 1.
    Goodwin K, Nelson C. Mechanics of Development. Dev Cell. 2021;56(2):240–250. PMCID: PMC8177046
    Reference Link
  • 1.
    Heimbucher T, Hog J, Gupta P, Murphy C. PQM-1 controls hypoxic survival via regulation of lipid metabolism. Nat Commun. 2020;11(1):4627. PMCID: PMC7532158
    Reference Link
  • 1.
    Song K, Cai X, Dong Y, Wu H, Wei Y, Shankavaram U, Cui K, Lee Y, Zhu B, Bhattacharjee S, Wang B, Zhang K, Wen A, Wong S, Yu L, Xia L, Welm A, Bielenberg D, Camphausen K, Kang Y, Chen H. Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development. J Clin Invest. 2021;131(1). PMCID: PMC7773373
    Reference Link
  • 1.
    Vrla G, Esposito M, Zhang C, Kang Y, Seyedsayamdost M, Gitai Z. Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa. PLoS Pathog. 2020;16(9):e1008867. PMCID: PMC7515202
    Reference Link
  • 1.
    Ravindran P, Wilson M, Jena S, Toettcher J. Engineering combinatorial and dynamic decoders using synthetic immediate-early genes. Commun Biol. 2020;3(1):436. PMCID: PMC7426417
    Reference Link
  • 1.
    Gil A, Carrasco-López C, Zhu L, Zhao E, Ravindran P, Wilson M, Goglia A, Avalos J, Toettcher J. Optogenetic control of protein binding using light-switchable nanobodies. Nat Commun. 2020;11(1):4044. PMCID: PMC7426870
    Reference Link
  • 1.
    Johnson H, Djabrayan N, Shvartsman S, Toettcher J. Optogenetic Rescue of a Patterning Mutant. Curr Biol. 2020;30(17):3414–3424.e3. PMCID: PMC7730203
    Reference Link
  • 1.
    Mashruwala A, Bassler B. The Vibrio cholerae Quorum-Sensing Protein VqmA Integrates Cell Density, Environmental, and Host-Derived Cues into the Control of Virulence. mBio. 2020;11(4). PMCID: PMC7387800
    Reference Link
  • 1.
    Merkle J, Wittes J, Schüpbach T. Signaling between somatic follicle cells and the germline patterns the egg and embryo of Drosophila. Curr Top Dev Biol. 2020;140:55–86. PMID: 32591083
    Reference Link
  • 1.
    Templeman N, Cota V, Keyes W, Kaletsky R, Murphy C. CREB Non-autonomously Controls Reproductive Aging through Hedgehog/Patched Signaling. Dev Cell. 2020;54(1):92–105.e5. PMCID: PMC7837322
    Reference Link
  • 1.
    Goodwin K, Nelson C. Branching morphogenesis. Development. 2020;147(10). PMID: 32444428
    Reference Link

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