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Saccharomyces cerevisiae Proteins

  • 1.
    Zhang Y, Cortez J, Hammer S, Carrasco-López C, Echauri S, Wiggins J, Wang W, Avalos J. Biosensor for branched-chain amino acid metabolism in yeast and applications in isobutanol and isopentanol production. Nat Commun. 2022;13(1):270. PMCID: PMC8755756
    Reference Link
  • 1.
    Nofal M, Wang T, Yang L, Jankowski C, Li S, Han S, Parsons L, Frese A, Gitai Z, Anthony T, Wühr M, Sabatini D, Rabinowitz J. GCN2 adapts protein synthesis to scavenging-dependent growth. Cell Syst. 2022;13(2):158–172.e9. PMCID: PMC8961722
    Reference Link
  • 1.
    Zhao E, Lalwani M, Chen J-M, Orillac P, Toettcher J, Avalos J. Optogenetic Amplification Circuits for Light-Induced Metabolic Control. ACS Synth Biol. 2021;10(5):1143–1154. PMCID: PMC8721662
    Reference Link
  • 1.
    Arlow T, Kim J, Haye-Bertolozzi J, Martínez C, Fay C, Zorensky E, Rose M, Gammie A. MutSα mismatch repair protein stability is governed by subunit interaction, acetylation, and ubiquitination. G3 (Bethesda). 2021;11(3). PMCID: PMC8063085
    Reference Link
  • 1.
    Wong S, Hepowit N, Port S, Yau R, Peng Y, Azad N, Habib A, Harpaz N, Schuldiner M, Hughson F, MacGurn J, Weisman L. Cargo Release from Myosin V Requires the Convergence of Parallel Pathways that Phosphorylate and Ubiquitylate the Cargo Adaptor. Curr Biol. 2020;30(22):4399–4412.e7. PMCID: PMC8025699
    Reference Link
  • 1.
    Luongo T, Eller J, Lu M-J, Niere M, Raith F, Perry C, Bornstein M, Oliphint P, Wang L, McReynolds M, Migaud M, Rabinowitz J, Johnson B, Johnsson K, Ziegler M, Cambronne X, Baur J. SLC25A51 is a mammalian mitochondrial NAD transporter. Nature. 2020;588(7836):174–179. PMCID: PMC7718333
    Reference Link
  • 1.
    Murawska M, Schauer T, Matsuda A, Wilson M, Pysik T, Wojcik F, Muir T, Hiraoka Y, Straub T, Ladurner A. The Chaperone FACT and Histone H2B Ubiquitination Maintain S. pombe Genome Architecture through Genic and Subtelomeric Functions. Mol Cell. 2020;77(3):501–513.e7. PMCID: PMC7007867
    Reference Link
  • 1.
    Gibney P, Chen A, Schieler A, Chen J, Xu Y, Hendrickson D, McIsaac S, Rabinowitz J, Botstein D. A tps1Δ persister-like state in Saccharomyces cerevisiae is regulated by MKT1. PLoS One. 2020;15(5):e0233779. PMCID: PMC7259636
    Reference Link
  • 1.
    Travis S, DAmico K, Yu I-M, McMahon C, Hamid S, Ramirez-Arellano G, Jeffrey P, Hughson F. Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1. J Biol Chem. 2020;295(30):10125–10135. PMCID: PMC7383367
    Reference Link
  • 1.
    Dao H, Dul B, Dann G, Liszczak G, Muir T. A basic motif anchoring ISWI to nucleosome acidic patch regulates nucleosome spacing. Nat Chem Biol. 2020;16(2):134–142. PMCID: PMC6982587
    Reference Link
  • 1.
    Garcia D, Leach R, Wadsworth G, Choudhary K, Li H, Aviran S, Kim H, Zakian V. Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP. Nat Commun. 2020;11(1):2173. PMCID: PMC7195438
    Reference Link
  • 1.
    Hammer S, Zhang Y, Avalos J. Mitochondrial Compartmentalization Confers Specificity to the 2-Ketoacid Recursive Pathway: Increasing Isopentanol Production in . ACS Synth Biol. 2020;9(3):546–555. PMID: 32049515
    Reference Link
  • 1.
    Travis S, Kokona B, Fairman R, Hughson F. Roles of singleton tryptophan motifs in COPI coat stability and vesicle tethering. Proc Natl Acad Sci U S A. 2019;116(48):24031–24040. PMCID: PMC6883825
    Reference Link
  • 1.
    Kuroda K, Hammer S, Watanabe Y, López J, Fink G, Stephanopoulos G, Ueda M, Avalos J. Critical Roles of the Pentose Phosphate Pathway and GLN3 in Isobutanol-Specific Tolerance in Yeast. Cell Syst. 2019;9(6):534–547.e5. PMID: 31734159
    Reference Link
  • 1.
    Chen C-F, Pohl T, Chan A, Slocum J, Zakian V. Centromere RNA Is Negatively Regulated by Cbf1 and Its Unscheduled Synthesis Impacts CenH3 Binding. Genetics. 2019;213(2):465–479. PMCID: PMC6781895
    Reference Link
  • 1.
    Pohl T, Zakian V. Pif1 family DNA helicases: A helpmate to RNase H?. DNA Repair (Amst). 2019;84:102633. PMCID: PMC6901714
    Reference Link
  • 1.
    Hall A, Rose M. Cell fusion in yeast is negatively regulated by components of the cell wall integrity pathway. Mol Biol Cell. 2019;30(4):441–452. PMCID: PMC6594448
    Reference Link
  • 1.
    Allard C, Decker F, Weiner O, Toettcher J, Graziano B. A size-invariant bud-duration timer enables robustness in yeast cell size control. PLoS One. 2018;13(12):e0209301. PMCID: PMC6303054
    Reference Link
  • 1.
    Tye B, Commins N, Ryazanova L, Wühr M, Springer M, Pincus D, Churchman S. Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness. Elife. 2019;8. PMCID: PMC6453566
    Reference Link
  • 1.
    Chen C-F, Pohl T, Pott S, Zakian V. Two Pif1 Family DNA Helicases Cooperate in Centromere Replication and Segregation in . Genetics. 2019;211(1):105–119. PMCID: PMC6325707
    Reference Link
  • 1.
    Jeon J, McGinty R, Muir T, Kim J-A, Kim J. Crosstalk among Set1 complex subunits involved in H2B ubiquitylation-dependent H3K4 methylation. Nucleic Acids Res. 2018;46(21):11129–11143. PMCID: PMC6265457
    Reference Link
  • 1.
    Xu Y-F, Lu W, Chen J, Johnson S, Gibney P, Thomas D, Brown G, May A, Campagna S, Yakunin A, Botstein D, Rabinowitz J. Discovery and Functional Characterization of a Yeast Sugar Alcohol Phosphatase. ACS Chem Biol. 2018;13(10):3011–3020. PMCID: PMC6466636
    Reference Link
  • 1.
    Geronimo C, Singh S, Galletto R, Zakian V. The signature motif of the Saccharomyces cerevisiae Pif1 DNA helicase is essential in vivo for mitochondrial and nuclear functions and in vitro for ATPase activity. Nucleic Acids Res. 2018;46(16):8357–8370. PMCID: PMC6144861
    Reference Link
  • 1.
    Hammer S, Avalos J. Uncovering the role of branched-chain amino acid transaminases in Saccharomyces cerevisiae isobutanol biosynthesis. Metab Eng. 2017;44:302–312. PMID: 29037781
    Reference Link
  • 1.
    Smith J, Hall A, Rose M. Membrane curvature directs the localization of Cdc42p to novel foci required for cell-cell fusion. J Cell Biol. 2017;216(12):3971–3980. PMCID: PMC5716282
    Reference Link
  • 1.
    Melloy P, Rose M. Influence of the bud neck on nuclear envelope fission in Saccharomyces cerevisiae. Exp Cell Res. 2017;358(2):390–396. PMCID: PMC6067115
    Reference Link
  • 1.
    Choi J, Rajagopal A, Xu Y-F, Rabinowitz J, O’Shea E. A systematic genetic screen for genes involved in sensing inorganic phosphate availability in Saccharomyces cerevisiae. PLoS One. 2017;12(5):e0176085. PMCID: PMC5435139
    Reference Link
  • 1.
    Geronimo C, Zakian V. Getting it done at the ends: Pif1 family DNA helicases and telomeres. DNA Repair (Amst). 2016;44:151–158. PMCID: PMC5441554
    Reference Link
  • 1.
    Tran P, Pohl T, Chen C-F, Chan A, Pott S, Zakian V. PIF1 family DNA helicases suppress R-loop mediated genome instability at tRNA genes. Nat Commun. 2017;8:15025. PMCID: PMC5413955
    Reference Link
  • 1.
    Hackett S, Zanotelli V, Xu W, Goya J, Park J, Perlman D, Gibney P, Botstein D, Storey J, Rabinowitz J. Systems-level analysis of mechanisms regulating yeast metabolic flux. Science. 2016;354(6311). PMCID: PMC5414049
    Reference Link
  • 1.
    Ha J, Chou H-T, Ungar D, Yip C, Walz T, Hughson F. Molecular architecture of the complete COG tethering complex. Nat Struct Mol Biol. 2016;23(8):758–60. PMCID: PMC4972656
    Reference Link
  • 1.
    Costanzo M, VanderSluis B, Koch E, Baryshnikova A, Pons C, Tan G, Wang W, Usaj M, Hanchard J, Lee S, Pelechano V, Styles E, Billmann M, van Leeuwen J, van Dyk N, Lin Z-Y, Kuzmin E, Nelson J, Piotrowski J, Srikumar T, Bahr S, Chen Y, Deshpande R, Kurat C, Li S, Li Z, Usaj M, Okada H, Pascoe N, San Luis B-J, Sharifpoor S, Shuteriqi E, Simpkins S, Snider J, Suresh H, Tan Y, Zhu H, Malod-Dognin N, Janjic V, Przulj N, Troyanskaya O, Stagljar I, Xia T, Ohya Y, Gingras A-C, Raught B, Boutros M, Steinmetz L, Moore C, Rosebrock A, Caudy A, Myers C, Andrews B, Boone C. A global genetic interaction network maps a wiring diagram of cellular function. Science. 2016;353(6306). PMCID: PMC5661885
    Reference Link
  • 1.
    Jonikas M, Collins S, Denic V, Oh E, Quan E, Schmid V, Weibezahn J, Schwappach B, Walter P, Weissman J, Schuldiner M. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science. 2009;323(5922):1693–7. PMCID: PMC2877488
    Reference Link
  • 1.
    Chung N, Storey J. Statistical significance of variables driving systematic variation in high-dimensional data. Bioinformatics. 2015;31(4):545–54. PMCID: PMC4325543
    Reference Link
  • 1.
    Pritykin Y, Ghersi D, Singh M. Genome-Wide Detection and Analysis of Multifunctional Genes. PLoS Comput Biol. 2015;11(10):e1004467. PMCID: PMC4593560
    Reference Link
  • 1.
    Baker R, Jeffrey P, Zick M, Phillips B, Wickner W, Hughson F. A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly. Science. 2015;349(6252):1111–4. PMCID: PMC4727825
    Reference Link
  • 1.
    Suckling R, Poon P, Travis S, Majoul I, Hughson F, Evans P, Duden R, Owen D. Structural basis for the binding of tryptophan-based motifs by δ-COP. Proc Natl Acad Sci U S A. 2015;112(46):14242–7. PMCID: PMC4655537
    Reference Link
  • 1.
    Rogers J, McMahon C, Baryshnikova A, Hughson F, Rose M. ER-associated retrograde SNAREs and the Dsl1 complex mediate an alternative, Sey1p-independent homotypic ER fusion pathway. Mol Biol Cell. 2014;25(21):3401–12. PMCID: PMC4214786
    Reference Link
  • 1.
    Rogers J, Rose M. Kar5p is required for multiple functions in both inner and outer nuclear envelope fusion in Saccharomyces cerevisiae. G3 (Bethesda). 2014;5(1):111–21. PMCID: PMC4291462
    Reference Link
  • 1.
    Kim J, Rose M. Stable Pseudohyphal Growth in Budding Yeast Induced by Synergism between Septin Defects and Altered MAP-kinase Signaling. PLoS Genet. 2015;11(12):e1005684. PMCID: PMC4671653
    Reference Link
  • 1.
    Stein R, Smith J, Rose M. An Amphiphysin-Like Domain in Fus2p Is Required for Rvs161p Interaction and Cortical Localization. G3 (Bethesda). 2015;6(2):337–49. PMCID: PMC4751553
    Reference Link
  • 1.
    Smith J, Rose M. Kel1p Mediates Yeast Cell Fusion Through a Fus2p- and Cdc42p-Dependent Mechanism. Genetics. 2016;202(4):1421–35. PMCID: PMC4905532
    Reference Link
  • 1.
    Lin K-W, McDonald K, Guise A, Chan A, Cristea I, Zakian V. Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length. Nat Commun. 2015;6:8290. PMCID: PMC4579843
    Reference Link
  • 1.
    Stundon J, Zakian V. Identification of Saccharomyces cerevisiae Genes Whose Deletion Causes Synthetic Effects in Cells with Reduced Levels of the Nuclear Pif1 DNA Helicase. G3 (Bethesda). 2015;5(12):2913–8. PMCID: PMC4683662
    Reference Link

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