Ellison C, Fei C, Dalia T, Wingreen N, Dalia A, Shaevitz J, Gitai Z. Subcellular localization of type IV pili regulates bacterial multicellular development. Nat Commun. 2022;13(1):6334. PMCID: PMC9596432

Taylor I, Murray-Nerger L, Greco T, Liu D, Cristea I, Bassler B. Protein Interaction Networks of Catalytically Active and Catalytically Inactive PqsE in Pseudomonas aeruginosa. mBio. 2022;13(5):e0155922. PMCID: PMC9600345

Taylor I, Jeffrey P, Moustafa D, Goldberg J, Bassler B. The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against . Biochemistry. 2022;61(17):1894–1903. PMCID: PMC9454246

Scheffler R, Bratton B, Gitai Z. Pseudomonas aeruginosa clinical blood isolates display significant phenotypic variability. PLoS One. 2022;17(7):e0270576. PMCID: PMC9258867

Koch M, Black M, Han E, Shaevitz J, Gitai Z. distinguishes surfaces by stiffness using retraction of type IV pili. Proc Natl Acad Sci U S A. 2022;119(20):e2119434119. PMCID: PMC9171759

Høyland-Kroghsbo N, Bassler B. Phage Infection Restores PQS Signaling and Enhances Growth of a Pseudomonas aeruginosa Quorum-Sensing Mutant. J Bacteriol. 2022;204(5):e0055721. PMCID: PMC9112912

Simanek K, Taylor I, Richael E, Lasek-Nesselquist E, Bassler B, Paczkowski J. The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in . Microbiol Spectr. 2022;10(1):e0210821. PMCID: PMC8754118

Moore R, Kaletsky R, Murphy C. Protocol for transgenerational learned pathogen avoidance behavior assays in . STAR Protoc. 2021;2(1):100384. PMCID: PMC7960678

Sivaloganathan D, Brynildsen M. Pseudomonas aeruginosa prioritizes detoxification of hydrogen peroxide over nitric oxide. BMC Res Notes. 2021;14(1):120. PMCID: PMC7995768

Taylor I, Paczkowski J, Jeffrey P, Henke B, Smith C, Bassler B. Inhibitor Mimetic Mutations in the PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production. ACS Chem Biol. 2021;16(4):740–752. PMCID: PMC8056388

Koch M, Fei C, Wingreen N, Shaevitz J, Gitai Z. Competitive binding of independent extension and retraction motors explains the quantitative dynamics of type IV pili. Proc Natl Acad Sci U S A. 2021;118(8). PMCID: PMC7923367

Scheffler R, Sugimoto Y, Bratton B, Ellison C, Koch M, Donia M, Gitai Z. Pseudomonas aeruginosa detachment from surfaces via a self-made small molecule. J Biol Chem. 2021;296:100279. PMCID: PMC7949062

Vrla G, Esposito M, Zhang C, Kang Y, Seyedsayamdost M, Gitai Z. Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa. PLoS Pathog. 2020;16(9):e1008867. PMCID: PMC7515202

Kaletsky R, Moore R, Vrla G, Parsons L, Gitai Z, Murphy C. C. elegans interprets bacterial non-coding RNAs to learn pathogenic avoidance. Nature. 2020;586(7829):445–451. PMCID: PMC8547118

Mukherjee S, Jemielita M, Stergioula V, Tikhonov M, Bassler B. Photosensing and quorum sensing are integrated to control Pseudomonas aeruginosa collective behaviors. PLoS Biol. 2019;17(12):e3000579. PMCID: PMC6932827

McCready A, Paczkowski J, Henke B, Bassler B. Structural determinants driving homoserine lactone ligand selection in the LasR quorum-sensing receptor. Proc Natl Acad Sci U S A. 2019;116(1):245–254. PMCID: PMC6320529

Martin J, Sheehan J, Bratton B, Moore G, Mateus A, Li S, Kim H, Rabinowitz J, Typas A, Savitski M, Wilson M, Gitai Z. A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance. Cell. 2020;181(7):1518–1532.e14. PMCID: PMC7780349

Valastyan J, Tota M, Taylor I, Stergioula V, Hone G, Smith C, Henke B, Carson K, Bassler B. Discovery of PqsE Thioesterase Inhibitors for Using DNA-Encoded Small Molecule Library Screening. ACS Chem Biol. 2020;15(2):446–456. PMCID: PMC7036018

Chuang S, Vrla G, Fröhlich K, Gitai Z. Surface association sensitizes Pseudomonas aeruginosa to quorum sensing. Nat Commun. 2019;10(1):4118. PMCID: PMC6739362

Moore R, Kaletsky R, Murphy C. Piwi/PRG-1 Argonaute and TGF-β Mediate Transgenerational Learned Pathogenic Avoidance. Cell. 2019;177(7):1827–1841.e12. PMCID: PMC7518193

McCready A, Paczkowski J, Cong J-P, Bassler B. An autoinducer-independent RhlR quorum-sensing receptor enables analysis of RhlR regulation. PLoS Pathog. 2019;15(6):e1007820. PMCID: PMC6564026

Sanfilippo J, Lorestani A, Koch M, Bratton B, Siryaporn A, Stone H, Gitai Z. Microfluidic-based transcriptomics reveal force-independent bacterial rheosensing. Nat Microbiol. 2019;4(8):1274–1281. PMCID: PMC6656604

Paczkowski J, McCready A, Cong J-P, Li Z, Jeffrey P, Smith C, Henke B, Hughson F, Bassler B. An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. ACS Chem Biol. 2019;14(3):378–389. PMCID: PMC6601336

Okada B, Li A, Seyedsayamdost M. Identification of the Hypertension Drug Guanfacine as an Antivirulence Agent in Pseudomonas aeruginosa. Chembiochem. 2019;20(15):2005–2011. PMCID: PMC6814388

Trivedi R, Crooks J, Auer G, Pendry J, Foik I, Siryaporn A, Abbott N, Gitai Z, Weibel D. Mechanical Genomic Studies Reveal the Role of d-Alanine Metabolism in Pseudomonas aeruginosa Cell Stiffness. mBio. 2018;9(5). PMCID: PMC6134093

Mukherjee S, Moustafa D, Stergioula V, Smith C, Goldberg J, Bassler B. The PqsE and RhlR proteins are an autoinducer synthase-receptor pair that control virulence and biofilm development in . Proc Natl Acad Sci U S A. 2018;115(40):E9411-E9418. PMCID: PMC6176596

Kannan A, Yang Z, Kim M, Stone H, Siryaporn A. Dynamic switching enables efficient bacterial colonization in flow. Proc Natl Acad Sci U S A. 2018;115(21):5438–5443. PMCID: PMC6003447

Mukherjee S, Moustafa D, Smith C, Goldberg J, Bassler B. The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer. PLoS Pathog. 2017;13(7):e1006504. PMCID: PMC5531660

Robinson J, Jaslove J, Murawski A, Fazen C, Brynildsen M. An integrated network analysis reveals that nitric oxide reductase prevents metabolic cycling of nitric oxide by Pseudomonas aeruginosa. Metab Eng. 2017;41:67–81. PMID: 28363762

Høyland-Kroghsbo N, Paczkowski J, Mukherjee S, Broniewski J, Westra E, Bondy-Denomy J, Bassler B. Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system. Proc Natl Acad Sci U S A. 2017;114(1):131–135. PMCID: PMC5224376

Paczkowski J, Mukherjee S, McCready A, Cong J-P, Aquino C, Kim H, Henke B, Smith C, Bassler B. Flavonoids Suppress Virulence through Allosteric Inhibition of Quorum-sensing Receptors. J Biol Chem. 2017;292(10):4064–4076. PMCID: PMC5354481

Nadell C, Ricaurte D, Yan J, Drescher K, Bassler B. Flow environment and matrix structure interact to determine spatial competition in biofilms. Elife. 2017;6. PMCID: PMC5283829

Inclan Y, Persat A, Greninger A, Von Dollen J, Johnson J, Krogan N, Gitai Z, Engel J. A scaffold protein connects type IV pili with the Chp chemosensory system to mediate activation of virulence signaling in Pseudomonas aeruginosa. Mol Microbiol. 2016;101(4):590–605. PMCID: PMC4980298

Robinson J, Brynildsen M. Discovery and dissection of metabolic oscillations in the microaerobic nitric oxide response network of Escherichia coli. Proc Natl Acad Sci U S A. 2016;113(12):E1757–66. PMCID: PMC4812703

Henry T, Brynildsen M. Quantifying Current Events Identifies a Novel Endurance Regulator. Trends Microbiol. 2016;24(5):324–326. PMCID: PMC4841710

Siryaporn A, Kim M, Shen Y, Stone H, Gitai Z. Colonization, competition, and dispersal of pathogens in fluid flow networks. Curr Biol. 2015;25(9):1201–7. PMCID: PMC4422760

Persat A, Inclan Y, Engel J, Stone H, Gitai Z. Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2015;112(24):7563–8. PMCID: PMC4475988

Rutherford S, Bassler B. Bacterial quorum sensing: its role in virulence and possibilities for its control. Cold Spring Harb Perspect Med. 2012;2(11). PMCID: PMC3543102

Drescher K, Shen Y, Bassler B, Stone H. Biofilm streamers cause catastrophic disruption of flow with consequences for environmental and medical systems. Proc Natl Acad Sci U S A. 2013;110(11):4345–50. PMCID: PMC3600445

O’Loughlin C, Miller L, Siryaporn A, Drescher K, Semmelhack M, Bassler B. A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proc Natl Acad Sci U S A. 2013;110(44):17981–6. PMCID: PMC3816427

Miller L, O’Loughlin C, Zhang Z, Siryaporn A, Silpe J, Bassler B, Semmelhack M. Development of potent inhibitors of pyocyanin production in Pseudomonas aeruginosa. J Med Chem. 2015;58(3):1298–306. PMCID: PMC4332565

Persat A, Nadell C, Kim M, Ingremeau F, Siryaporn A, Drescher K, Wingreen N, Bassler B, Gitai Z, Stone H. The mechanical world of bacteria. Cell. 2015;161(5):988–997. PMCID: PMC4451180