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Protein Serine-Threonine Kinases

  • 1.
    Nofal M, Wang T, Yang L, Jankowski C, Li S, Han S, Parsons L, Frese A, Gitai Z, Anthony T, Wühr M, Sabatini D, Rabinowitz J. GCN2 adapts protein synthesis to scavenging-dependent growth. Cell Syst. 2022;13(2):158–172.e9. PMCID: PMC8961722
    Reference Link
  • 1.
    Rabie E, Zhang S, Dunn C, Nelson C. Substratum stiffness signals through integrin-linked kinase and β1-integrin to regulate midbody proteins and abscission during EMT. Mol Biol Cell. 2021;32(18):1664–1676. PMCID: PMC8684726
    Reference Link
  • 1.
    Yu D, Richardson N, Green C, Spicer A, Murphy M, Flores V, Jang C, Kasza I, Nikodemova M, Wakai M, Tomasiewicz J, Yang S, Miller B, Pak H, Brinkman J, Rojas J, Quinn W, Cheng E, Konon E, Haider L, Finke M, Sonsalla M, Alexander C, Rabinowitz J, Baur J, Malecki K, Lamming D. The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine. Cell Metab. 2021;33(5):905–922.e6. PMCID: PMC8102360
    Reference Link
  • 1.
    Van Cleemput J, Koyuncu O, Laval K, Engel E, Enquist L. CRISPR/Cas9-Constructed Pseudorabies Virus Mutants Reveal the Importance of UL13 in Alphaherpesvirus Escape from Genome Silencing. J Virol. 2021;95(6). PMCID: PMC8094956
    Reference Link
  • 1.
    Kilinc A, Han S, Barrett L, Anandasivam N, Nelson C. Integrin-linked kinase tunes cell-cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ1. Mol Biol Cell. 2021;32(5):402–412. PMCID: PMC8098849
    Reference Link
  • 1.
    Anlas A, Nelson C. Soft Microenvironments Induce Chemoresistance by Increasing Autophagy Downstream of Integrin-Linked Kinase. Cancer Res. 2020;80(19):4103–4113. PMCID: PMC7534696
    Reference Link
  • 1.
    Albig C, Wang C, Dann G, Wojcik F, Schauer T, Krause S, Maenner S, Cai W, Li Y, Girton J, Muir T, Johansen J, Johansen K, Becker P, Regnard C. JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila. Nat Commun. 2019;10(1):5343. PMCID: PMC6877644
    Reference Link
  • 1.
    Adamson B, Norman T, Jost M, Cho M, Nuñez J, Chen Y, Villalta J, Gilbert L, Horlbeck M, Hein M, Pak R, Gray A, Gross C, Dixit A, Parnas O, Regev A iv, Weissman J. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016;167(7):1867–1882.e21. PMCID: PMC5315571
    Reference Link
  • 1.
    Han S, Pang M-F, Nelson C. Substratum stiffness tunes proliferation downstream of Wnt3a in part by regulating integrin-linked kinase and frizzled-1. J Cell Sci. 2018;131(8). PMCID: PMC5963841
    Reference Link
  • 1.
    Liu L, Rowe G, Yang S, Li J, Damilano F, Chan M, Lu W, Jang C, Wada S, Morley M, Hesse M, Fleischmann B, Rabinowitz J, Das S, Rosenzweig A, Arany Z. PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy. Circ Res. 2017;121(12):1370–1378. PMCID: PMC5722682
    Reference Link
  • 1.
    Jin L, Chun J, Pan C, Kumar A, Zhang G, Ha Y, Li D, Alesi G, Kang Y, Zhou L, Yu W-M, Magliocca K, Khuri F, Qu C-K, Metallo C, Owonikoko T, Kang S. The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer. Mol Cell. 2018;69(1):87–99.e7. PMCID: PMC5777230
    Reference Link
  • 1.
    Lee G, Zheng Y, Cho S, Jang C, England C, Dempsey J, Yu Y, Liu X, He L, Cavaliere P, Chavez A, Zhang E, Isik M, Couvillon A, Dephoure N, Blackwell K, Yu J, Rabinowitz J, Cantley L, Blenis J. Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling. Cell. 2017;171(7):1545–1558.e18. PMCID: PMC5920692
    Reference Link
  • 1.
    Chikina M, Gerald C, Li X, Ge Y, Pincas H, Nair V, Wong A, Krishnan A, Troyanskaya O, Raymond D, Saunders-Pullman R, Bressman S, Yue Z, Sealfon S. Low-variance RNAs identify Parkinson’s disease molecular signature in blood. Mov Disord. 2015;30(6):813–21. PMCID: PMC4439364
    Reference Link
  • 1.
    Christensen M, Jensen S, Miettinen J, Luecke S, Prabakaran T, Reinert L, Mettenleiter T, Chen Z, Knipe D, Sandri-Goldin R, Enquist L, Hartmann R, Mogensen T, Rice S, Nyman T, Matikainen S, Paludan S. HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression. EMBO J. 2016;35(13):1385–99. PMCID: PMC4931188
    Reference Link
  • 1.
    Pang M-F, Siedlik M, Han S, Stallings-Mann M, Radisky D, Nelson C. Tissue Stiffness and Hypoxia Modulate the Integrin-Linked Kinase ILK to Control Breast Cancer Stem-like Cells. Cancer Res. 2016;76(18):5277–87. PMCID: PMC5026611
    Reference Link
  • 1.
    Yang L, Paul S, Trieu K, Dent L, Froldi F, Forés M, Webster K, Siegfried K, Kondo S, Harvey K, Cheng L, Jiménez G, Shvartsman S, Veraksa A. Minibrain and Wings apart control organ growth and tissue patterning through down-regulation of Capicua. Proc Natl Acad Sci U S A. 2016;113(38):10583–8. PMCID: PMC5035877
    Reference Link
  • 1.
    Shrestha R, Little K, Tamayo J, Li W, Perlman D, Devenport D. Mitotic Control of Planar Cell Polarity by Polo-like Kinase 1. Dev Cell. 2015;33(5):522–34. PMCID: PMC4464975
    Reference Link
  • 1.
    Korennykh A, Walter P. Structural basis of the unfolded protein response. Annu Rev Cell Dev Biol. 2012;28:251–77. PMID: 23057742
    Reference Link

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