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Protein Folding

  • 1.
    Doyle M, Jimah J, Dowdy T, Ohlemacher S, Larion M, Hinshaw J, Bernstein H. Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding. Cell. 2022;185(7):1143–1156.e13. PMCID: PMC8985213
    Reference Link
  • 1.
    Combs A, Silhavy T. The sacrificial adaptor protein Skp functions to remove stalled substrates from the β-barrel assembly machine. Proc Natl Acad Sci U S A. 2022;119(1). PMCID: PMC8740687
    Reference Link
  • 1.
    Yan R, Cao P, Song W, Li Y, Wang T, Qian H, Yan C, Yan N. Structural basis for sterol sensing by Scap and Insig. Cell Rep. 2021;35(13):109299. PMID: 34192549
    Reference Link
  • 1.
    Zhang Y, Hughson F. Chaperoning SNARE Folding and Assembly. Annu Rev Biochem. 2021;90:581–603. PMCID: PMC8900292
    Reference Link
  • 1.
    Thomas C, Aller S, Beis K, Carpenter E, Chang G, Chen L, Dassa E, Dean M, Van Hoa F, Ekiert D, Ford R, Gaudet R, Gong X, Holland B, Huang Y, Kahne D, Kato H, Koronakis V, Koth C, Lee Y, Lewinson O, Lill R, Martinoia E, Murakami S, Pinkett H, Poolman B, Rosenbaum D, Sarkadi B, Schmitt L, Schneider E, Shi Y, Shyng S-L, Slotboom D, Tajkhorshid E, Tieleman P, Ueda K, Váradi A, Wen P-C, Yan N, Zhang P, Zheng H, Zimmer J, Tampé R. Structural and functional diversity calls for a new classification of ABC transporters. FEBS Lett. 2020;594(23):3767–3775. PMCID: PMC8386196
    Reference Link
  • 1.
    Hart E, Silhavy T. Functions of the BamBCDE Lipoproteins Revealed by Bypass Mutations in BamA. J Bacteriol. 2020;202(21). PMCID: PMC7549358
    Reference Link
  • 1.
    Stevens A, Sekar G, Gramespacher J, Cowburn D, Muir T. An Atypical Mechanism of Split Intein Molecular Recognition and Folding. J Am Chem Soc. 2018;140(37):11791–11799. PMCID: PMC7232844
    Reference Link
  • 1.
    Ricci D, Silhavy T. Outer Membrane Protein Insertion by the β-barrel Assembly Machine. EcoSal Plus. 2019;8(2). PMCID: PMC6419762
    Reference Link
  • 1.
    Carey J. Globularity and protein function. J Biomol Struct Dyn. 2000;17 Suppl 1:87–8. PMID: 22607410
    Reference Link
  • 1.
    Lee J, Sutterlin H, Wzorek J, Mandler M, Hagan C, Grabowicz M, Tomasek D, May M, Hart E, Silhavy T, Kahne D. Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion. Proc Natl Acad Sci U S A. 2018;115(10):2359–2364. PMCID: PMC5877925
    Reference Link
  • 1.
    Hecht M, Zarzhitsky S, Karas C, Chari S. Are natural proteins special? Can we do that?. Curr Opin Struct Biol. 2018;48:124–132. PMID: 29306103
    Reference Link
  • 1.
    Donnelly A, Murphy G, Digianantonio K, Hecht M. A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli. Nat Chem Biol. 2018;14(3):253–255. PMID: 29334382
    Reference Link
  • 1.
    Lu F, Li S, Jiang Y, Jiang J, Fan H, Lu G, Deng D, Dang S, Zhang X, Wang J, Yan N. Structure and mechanism of the uracil transporter UraA. Nature. 2011;472(7342):243–6. PMID: 21423164
    Reference Link
  • 1.
    Mahoney T, Ricci D, Silhavy T. Classifying β-Barrel Assembly Substrates by Manipulating Essential Bam Complex Members. J Bacteriol. 2016;198(14):1984–92. PMCID: PMC4936103
    Reference Link
  • 1.
    Grabowicz M, Koren D, Silhavy T. The CpxQ sRNA Negatively Regulates Skp To Prevent Mistargeting of β-Barrel Outer Membrane Proteins into the Cytoplasmic Membrane. mBio. 2016;7(2):e00312–16. PMCID: PMC4817254
    Reference Link
  • 1.
    Lee J, Xue M, Wzorek J, Wu T, Grabowicz M, Gronenberg L, Sutterlin H, Davis R, Ruiz N, Silhavy T, Kahne D. Characterization of a stalled complex on the β-barrel assembly machine. Proc Natl Acad Sci U S A. 2016;113(31):8717–22. PMCID: PMC4978274
    Reference Link
  • 1.
    Jonikas M, Collins S, Denic V, Oh E, Quan E, Schmid V, Weibezahn J, Schwappach B, Walter P, Weissman J, Schuldiner M. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science. 2009;323(5922):1693–7. PMCID: PMC2877488
    Reference Link
  • 1.
    Carey J, Brynda J, Wolfová J, Grandori R, Gustavsson T, Ettrich R, Smatanová I. WrbA bridges bacterial flavodoxins and eukaryotic NAD(P)H:quinone oxidoreductases. Protein Sci. 2007;16(10):2301–5. PMCID: PMC2204128
    Reference Link
  • 1.
    Carey J, Lindman S, Bauer M, Linse S. Protein reconstitution and three-dimensional domain swapping: benefits and constraints of covalency. Protein Sci. 2007;16(11):2317–33. PMCID: PMC2211703
    Reference Link
  • 1.
    Neiditch M, Federle M, Miller S, Bassler B, Hughson F. Regulation of LuxPQ receptor activity by the quorum-sensing signal autoinducer-2. Mol Cell. 2005;18(5):507–18. PMID: 15916958
    Reference Link

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